ID A0A6G0UM27_9BILA Unreviewed; 160 AA.
AC A0A6G0UM27;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE RecName: Full=Mitochondrial fission factor {ECO:0000256|RuleBase:RU368040};
GN ORFNames=FO519_006611 {ECO:0000313|EMBL:KAE9550171.1};
OS Halicephalobus sp. NKZ332.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Panagrolaimoidea; Panagrolaimidae;
OC Halicephalobus.
OX NCBI_TaxID=2598192 {ECO:0000313|EMBL:KAE9550171.1, ECO:0000313|Proteomes:UP000488831};
RN [1] {ECO:0000313|EMBL:KAE9550171.1, ECO:0000313|Proteomes:UP000488831}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NKZ332 {ECO:0000313|EMBL:KAE9550171.1};
RC TISSUE=Whole-body {ECO:0000313|EMBL:KAE9550171.1};
RX PubMed=31814372;
RA Ragsdale E.J., Koutsovoulos G., Biddle J.F.;
RT "A draft genome for a species of Halicephalobus (Panagrolaimidae).";
RL J. Nematol. 51:1-4(2019).
CC -!- FUNCTION: Plays a role in mitochondrial and peroxisomal fission.
CC Promotes the recruitment and association of the fission mediator
CC dynamin-related protein 1 (DNM1L) to the mitochondrial surface.
CC {ECO:0000256|RuleBase:RU368040}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC {ECO:0000256|RuleBase:RU368040}; Single-pass type IV membrane protein
CC {ECO:0000256|RuleBase:RU368040}. Peroxisome
CC {ECO:0000256|RuleBase:RU368040}.
CC -!- SIMILARITY: Belongs to the Tango11 family.
CC {ECO:0000256|RuleBase:RU368040}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE9550171.1}.
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DR EMBL; VOSG01000311; KAE9550171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6G0UM27; -.
DR Proteomes; UP000488831; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0000266; P:mitochondrial fission; IEA:UniProtKB-UniRule.
DR GO; GO:0090141; P:positive regulation of mitochondrial fission; IEA:UniProtKB-UniRule.
DR GO; GO:0090314; P:positive regulation of protein targeting to membrane; IEA:UniProtKB-UniRule.
DR InterPro; IPR008518; Mff/Tango-11.
DR PANTHER; PTHR16501:SF6; TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11; 1.
DR PANTHER; PTHR16501; UNCHARACTERIZED; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU368040};
KW Mitochondrion {ECO:0000256|RuleBase:RU368040};
KW Mitochondrion outer membrane {ECO:0000256|RuleBase:RU368040};
KW Peroxisome {ECO:0000256|RuleBase:RU368040};
KW Reference proteome {ECO:0000313|Proteomes:UP000488831};
KW Transmembrane {ECO:0000256|RuleBase:RU368040};
KW Transmembrane helix {ECO:0000256|RuleBase:RU368040}.
FT TRANSMEM 136..153
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU368040"
SQ SEQUENCE 160 AA; 18055 MW; 16A0E8BB161A8AAD CRC64;
MTLAKAGVME VPEHIYVNGR NPGRNSAEFL AKEAAMIERG MRMPDQIVYE GNRASRGDDV
YDVNNQMRVP ETLTIHDLQM EDTVGRSDSH ASDNSIAVDE NPLRELKIMR RQLARLATRM
TVMEEANARR GTRETGLWLT TFGAIIAAAF FLLRKRITGF
//
