ID A0A6G0V7F7_9BILA Unreviewed; 567 AA.
AC A0A6G0V7F7;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216};
GN ORFNames=FO519_000422 {ECO:0000313|EMBL:KAE9556382.1};
OS Halicephalobus sp. NKZ332.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Panagrolaimoidea; Panagrolaimidae;
OC Halicephalobus.
OX NCBI_TaxID=2598192 {ECO:0000313|EMBL:KAE9556382.1, ECO:0000313|Proteomes:UP000488831};
RN [1] {ECO:0000313|EMBL:KAE9556382.1, ECO:0000313|Proteomes:UP000488831}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NKZ332 {ECO:0000313|EMBL:KAE9556382.1};
RC TISSUE=Whole-body {ECO:0000313|EMBL:KAE9556382.1};
RX PubMed=31814372;
RA Ragsdale E.J., Koutsovoulos G., Biddle J.F.;
RT "A draft genome for a species of Halicephalobus (Panagrolaimidae).";
RL J. Nematol. 51:1-4(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148,
CC ECO:0000256|RuleBase:RU361216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAE9556382.1}.
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DR EMBL; VOSG01000004; KAE9556382.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6G0V7F7; -.
DR Proteomes; UP000488831; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:1902475; P:L-alpha-amino acid transmembrane transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR11958:SF46; SODIUM-DEPENDENT EXCITATORY AMINO ACID TRANSPORTER GLT-3-RELATED; 1.
DR PANTHER; PTHR11958; SODIUM/DICARBOXYLATE SYMPORTER-RELATED; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361216};
KW Reference proteome {ECO:0000313|Proteomes:UP000488831};
KW Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|RuleBase:RU361216};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361216};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361216};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361216}.
FT TRANSMEM 5..26
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 176..195
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 216..237
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 249..275
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 287..308
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 328..349
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT REGION 485..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 567 AA; 62331 MW; 93E42DD8C3C4225C CRC64;
MKKDLLLVLT IESVVIGVVL GFVIRPFNPS LIGFPGEIFM QIVEMMILPM IISSVISALS
QIRPSDTSRI GTYTIVYYMT GIVLVSSIHP GDPALFHNLG EGTLDDTALS TLDTFLDQIR
NMFPENIIQA TFQQVQTNYI PVKPRLQRIN LNGTNMAENS TIIPLMKPIL EYTNEMNVLG
LIVFCTGFGI VLSILGDQAK LMINFFIVLD AVIMKWISAL MWCYPIGILS LVCKNIVDID
NLAETAQALA MYVVTVICGL MIHSLLTLPL LYYIFTRHSP FNFMTGMLQA LATAFGTASS
GATLPVTFRS LEENLKIDRR VTRFVLPLGA TITMDGTALY EAVAVIFIAQ LHNIQLTMFE
LLTISFTTTI ASIGSGSVPA GLDTILIVLT TVGLPAKDLS LLLTVDWLLD RIRTSVNVLG
DGFGCGIIYH LSKARLQEAD NDELIRQIKN DIQLLNAEIP TVVTPKLSLG VPPLTNINSQ
SQPLLTKQTS FDGGPRGSRI PMNAPKRRHS QQPFFYKSRQ GQLTIPIPST CSTPATNSGL
TSQNRKNSSH SMEERRSLLD GSLEFTV
//
