ID A0A6G1F446_9ORYZ Unreviewed; 1547 AA.
AC A0A6G1F446;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=tRNA(adenine(34)) deaminase {ECO:0000256|ARBA:ARBA00012740};
DE EC=3.5.4.33 {ECO:0000256|ARBA:ARBA00012740};
GN ORFNames=E2562_005606 {ECO:0000313|EMBL:KAF0931651.1};
OS Oryza meyeriana var. granulata.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza meyeriana.
OX NCBI_TaxID=110450 {ECO:0000313|EMBL:KAF0931651.1, ECO:0000313|Proteomes:UP000479710};
RN [1] {ECO:0000313|EMBL:KAF0931651.1, ECO:0000313|Proteomes:UP000479710}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Menghai {ECO:0000313|Proteomes:UP000479710};
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF0931651.1};
RA Li W.;
RT "Whole genome sequence of Oryza granulata.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA +
CC NH4(+); Xref=Rhea:RHEA:43168, Rhea:RHEA-COMP:10373, Rhea:RHEA-
CC COMP:10374, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:28938,
CC ChEBI:CHEBI:74411, ChEBI:CHEBI:82852; EC=3.5.4.33;
CC Evidence={ECO:0000256|ARBA:ARBA00001103};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAF0931651.1}.
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DR EMBL; SPHZ02000001; KAF0931651.1; -; Genomic_DNA.
DR Proteomes; UP000479710; Unassembled WGS sequence.
DR GO; GO:0052717; F:tRNA-specific adenosine-34 deaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0002100; P:tRNA wobble adenosine to inosine editing; IEA:InterPro.
DR CDD; cd01285; nucleoside_deaminase; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR InterPro; IPR002125; CMP_dCMP_dom.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR InterPro; IPR028883; tRNA_aden_deaminase.
DR PANTHER; PTHR11079:SF179; CYTOSINE DEAMINASE; 1.
DR PANTHER; PTHR11079; CYTOSINE DEAMINASE FAMILY MEMBER; 1.
DR Pfam; PF14437; MafB19-deam; 1.
DR SUPFAM; SSF53927; Cytidine deaminase-like; 1.
DR PROSITE; PS51747; CYT_DCMP_DEAMINASES_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000479710};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 1400..1512
FT /note="CMP/dCMP-type deaminase"
FT /evidence="ECO:0000259|PROSITE:PS51747"
FT REGION 243..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 530..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 962..990
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1023..1092
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1119..1243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..405
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..596
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 971..990
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1065
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1078..1092
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1129..1149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1150..1169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1183..1207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1208..1222
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1228..1243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1547 AA; 175425 MW; 6AADBE59C23981B6 CRC64;
MYSSYSAAAA LALRAAKPSS YHHYHHHHGD GECHQQQELL PLNPPRVAPR FMLDGYLLRH
SAHLLLLSAR LRPPPPPHPP THCCRRRVAA RCCGCYSGGS CGAGSRSIVG HVSWRLDPWG
CRCGGHGAGR SDLGVVCRRP EPRECRCGGG RLDLGASCGR RDAPRLVGRA VRQEVWEYEG
GEWPRTSCSM ECHADWEDEE DDCGLVQWEA PRRFHLSRTR WEEDDGDRCR DCHRRKGVEG
DYYDEDKYGG QRREKRNMNE RHGRFRDSDQ RGWEQRDYHD DDYYLEFRRW KERRDRRDTD
FDDAVARRGV EDRRYSKDDR KYDQRRERRD FGYEGAVGFR RGGTGRYTEN NQRSDWRTEN
RDYEVDEVDV RREGRHRTND DQTYVTQHQQ RTDDREEEDV SLLESPRWHD EEYEYDDRDI
SERRYYSGRS HKSARASALH DDESHRVSSS RNTADTRIAR NEDNSTSRVR WHDIVDRQAE
QTSEERDQRY SSSVGRSYDE KHDFSHDDAQ LVRLRDSRIG TQDVRVITED DTNLASSSKN
TTISKNHSTV DQKSTTRKDD SRKSSQKIME LSEVRGTNTE HDSRTQSHHQ ENRGRYIENR
SSSLQSSVKV ASDTRTQLDQ HDEVDQQVVA LTDSRRWSEK LTDIKMDSTC DVSRTSLTQR
NYDEVNQTDI DDRSTSVHNI THITRDKKTY VNQQVIHETD IDVQSVKHVD VSKVRASDIS
VSRNSQNHLE TRSDVANNQL EQTHASSSPM IRGPKGHLEA GLHNQVYSSS AAHIVNPTVG
KHEQVEFTNA RTNNTAIAST SESHIQTRID DQLQSTSAVN TFGGVQEQID LTKISTDSNV
ISSSQGLDTR GSQIGITSTR NFVDRTRESR DKSDQQLTQV INIDINDRVR SKFYESSKDS
IERLARLEET GRLMQHNMGL NWQQVGSSRI SDDTDIPTLE IQNTEDGSSM VTADVQKRPM
LMESSEQEER SETTAGNSIP SGSSARQPVN ESLLESAARL EKSSTFHVGQ FVGEVRKGVS
DADTNLTRKN VKSTMGSITR SSSRSRMRGP SNEMWDVQSA TSQETFKTAD KEEGSSVDEG
TTSTSQTPTN ETALAKKVHK SLWAYVADII RVGWIQRGES HDSDNNRSVK RSSSSNSQNT
EGWFSSQERD NEGIQKKNES SKPKDQYLMK SHTGEPLMKE SLPTGSQGLQ SSEAGNVCQT
GTSKGEFVSR SSKDDPHMTG EKAKQSDVAA SPRQNIVGGF SEDSTPTLVD VTLEHFPEHE
AATPSMIMTK GSADNETGNG VIAGTSSMPI NTEGVGWTAG SDDWRYDPSG AMTPYRHPHT
QVMMPHGDTS AVIQESPELP TGGSTRFDEK IVVQEAPEFI RTEGKDAELK RRKFQRNKQV
MKETFDEWEE AYQRDAEQRK TDELFMREAL HEAQRAADMW EVPVGAVLVQ NGEIIARGCN
LVEDLRDSTA HAEIVCIREA SNKLKTWRLA DTTLYVTLEP CAMCAGAILQ ARVDTVVWGA
PNKLLGADGS WVSICLSFCN FERFNRLTWS PILLTVNCAC FIFLKYL
//
