ID A0A6H5KZU7_9PHAE Unreviewed; 1039 AA.
AC A0A6H5KZU7;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Rad4 beta-hairpin domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ESUBFT_726_6 {ECO:0000313|EMBL:CAB1118156.1};
OS Ectocarpus sp. CCAP 1310/34.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=867726 {ECO:0000313|EMBL:CAB1118156.1, ECO:0000313|Proteomes:UP000485383};
RN [1] {ECO:0000313|Proteomes:UP000485383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bft15b / CCAP1310/34 {ECO:0000313|Proteomes:UP000485383};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAB1118156.1}.
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DR EMBL; CACKRE030004973; CAB1118156.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6H5KZU7; -.
DR Proteomes; UP000485383; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000485383}.
FT DOMAIN 808..859
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 919..995
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 1..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 173..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..42
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..423
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..493
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1039 AA; 110330 MW; 5F1095EEC9A17336 CRC64;
MSIHMMDDEE DDDIGWEDDD GQEIDDEGIA WEEDDDEGDG DGDDSGRGSN SGSVAAGGPA
GCAEFEEDDL EEEPEERRWL GDNGEIVVEL PRGEDEEGED GDDDGGRGGE SSSAGKGKGK
KKAKARRFTA ALSVHKAHLA CLVARCAMVS RWAGDPTVQA AIVSCLPNHL AKKHVPARQK
RNRQDSSSLP AVGDRDGGAA AAAAAAKKTK KKRKKDGDDD EEGTREDEEE DKMPSDGGNQ
LRLADLVVWF REFITVLDDG AVGGSEGSWG SRPQRLLRVI EQQAGCAQEA VQLFVSLCRG
LGLRARYVAC LDPVPPSPAA GLRRQPPPSK QTRNYTVNLA AAPAVLAEGK QGVRHHHRQR
RWGSGESGGG LQAAGGVGVG SSQAWAEVLC REGKELELSP SRRPPSSSPP PPPPPPPAPA
TSPRRPSKRQ RTRGTPEACL PPRDSRPKGS AGMPGGGGNS SRSRTEALSM NSDDEDSNGA
GAAESDDDDD DGARQLAEEQ RRQNRTSEKV DVDPPPGEST ATATLSGARA RPTRAGSKRN
ATGAIAAAET CTRPSNGSRR ELPRSREAAS SAAGASGTAH KTKRVAGAPK GEGFRDAVPC
NTAYPTGGTG GGTSADDGEA TANGARGVGV ADGGGGGKKG GRRGSGSSGG GAGANGSAAG
AAVAAAAGVS SCPSTRGGDR ERWIHVDPVV GALDQADKVQ ELRFRKRLMP YVVAEDEKKL
IVDVTRRYSS EWARTLRTRG RAMASADGWW NRSMRKWGAS ADRRSRRKVI GTGAASSPLV
VEGQRDDEAN EDGDQGASEE KELQEKVDKE PVPNTIAALK NHHKYVLGKK LLKFEALRPG
AKAAGLVKGS KVYLKTDVAT LRGASRWKKD ALQVKKSELD KPVKLATKKG EKEGEGTSKL
YGDWQTEPWA PEAAVDGKVP KNEYGNLEFF DCSPAFLPTG TAHLRGEQIG RLAAKLGVDY
APALTGFETK VGRQVPVLDG IIVCKEQSQM LRDAHMTWQQ MQLEKQVKVR GERVLRRWRT
LFKGVLLGAQ LLEEYGSHE
//
