ID A0A6I1F2W0_9BACI Unreviewed; 463 AA.
AC A0A6I1F2W0;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 24-JAN-2024, entry version 7.
DE RecName: Full=L-cystine uptake protein TcyP {ECO:0000256|ARBA:ARBA00022031};
DE AltName: Full=Transporter of cystine TcyP {ECO:0000256|ARBA:ARBA00031293};
GN ORFNames=F9279_18175 {ECO:0000313|EMBL:KAB7666320.1};
OS Bacillus sp. B1-b2.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2653201 {ECO:0000313|EMBL:KAB7666320.1, ECO:0000313|Proteomes:UP000437773};
RN [1] {ECO:0000313|EMBL:KAB7666320.1, ECO:0000313|Proteomes:UP000437773}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B1-b2 {ECO:0000313|EMBL:KAB7666320.1,
RC ECO:0000313|Proteomes:UP000437773};
RA Park S.-J.;
RT "Draft genome sequence of Bacillus sp. B1-b2.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KAB7666320.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; WEHU01000021; KAB7666320.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6I1F2W0; -.
DR Proteomes; UP000437773; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF5; L-CYSTINE TRANSPORTER TCYP; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000437773};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 463 AA; 49058 MW; DAE4FD44FEB9D791 CRC64;
MNLYVILNII ILLLLLGVLY YMQKKHVSFS KRVFTGLGLG IVFGVILQLI YEPGTETITA
TSDWFSLIGS GYVKLLQMIV MPLVLVSIIS AFTRLQKSAN LGKISGLVIG TLLITTAISA
AIGIAAATGF DLKAIDVNAG DTEVLRGQQL EESLGEVEST TIPQKILGFL PANPFQDLTG
ARPTSTIAVV IFAAFIGVAY LGIKRKNPEQ AEFFQKIIEA VHSIVMRIVT LVLRLTPYGI
LALMTKTVAG SDFAAIAKLG KFVLASYVAL IAMFIVHLII LALFKLSPKQ YVQKVMPVLS
FAFTSRTSAG TMPLNIDAQK NKLGVPESIA NFSASFGVSI GQNGCAGIYP AMLAVMIAPT
QGIDPLSPSF IATLIAVVMI SSFGVAGVGG GATFATLIVL STMNFPVALA GVLISVEPLI
DMGRTALNVS GSMVSGLVTS KTLGELDMKK YNEKNIDPSE NVA
//
