ID A0A6I5CR02_9ACTN Unreviewed; 140 AA.
AC A0A6I5CR02;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 27-MAR-2024, entry version 10.
DE RecName: Full=Anti-sigma factor antagonist {ECO:0000256|RuleBase:RU003749};
GN ORFNames=GTY54_45950 {ECO:0000313|EMBL:MYR63243.1};
OS Streptomyces sp. SID625.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2690321 {ECO:0000313|EMBL:MYR63243.1, ECO:0000313|Proteomes:UP000469395};
RN [1] {ECO:0000313|EMBL:MYR63243.1, ECO:0000313|Proteomes:UP000469395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SID625 {ECO:0000313|EMBL:MYR63243.1,
RC ECO:0000313|Proteomes:UP000469395};
RX PubMed=30705269; DOI=.1038/s41467-019-08438-0;
RA Chevrette M.G., Carlson C.M., Ortega H.E., Thomas C., Ananiev G.E.,
RA Barns K.J., Book A.J., Cagnazzo J., Carlos C., Flanigan W., Grubbs K.J.,
RA Horn H.A., Hoffmann F.M., Klassen J.L., Knack J.J., Lewin G.R.,
RA McDonald B.R., Muller L., Melo W.G.P., Pinto-Tomas A.A., Schmitz A.,
RA Wendt-Pienkowski E., Wildman S., Zhao M., Zhang F., Bugni T.S., Andes D.R.,
RA Pupo M.T., Currie C.R.;
RT "The antimicrobial potential of Streptomyces from insect microbiomes.";
RL Nat. Commun. 10:516-516(2019).
CC -!- SIMILARITY: Belongs to the anti-sigma-factor antagonist family.
CC {ECO:0000256|ARBA:ARBA00009013, ECO:0000256|RuleBase:RU003749}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MYR63243.1}.
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DR EMBL; WWHO01004232; MYR63243.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A6I5CR02; -.
DR Proteomes; UP000469395; Unassembled WGS sequence.
DR GO; GO:0043856; F:anti-sigma factor antagonist activity; IEA:InterPro.
DR CDD; cd07043; STAS_anti-anti-sigma_factors; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR003658; Anti-sigma_ant.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00377; ant_ant_sig; 1.
DR PANTHER; PTHR33495; ANTI-SIGMA FACTOR ANTAGONIST TM_1081-RELATED-RELATED; 1.
DR PANTHER; PTHR33495:SF2; ANTI-SIGMA-B FACTOR ANTAGONIST; 1.
DR Pfam; PF01740; STAS; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000469395}.
FT DOMAIN 14..123
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT REGION 120..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 140 AA; 14244 MW; 4598B2971ED6A172 CRC64;
MDRGTVGSAQ SGRLLVEVRQ EGSSAVVTPA GELDHHTADL LREPLEECLD KGRSRLVVDC
SRLDFCDSTG LNVLLGARLK AEAAGGGVHL AGMLPVVARV FEITGADAVF TVHATLDDAL
AGERGGPGAP GRDGEAGGAG
//
