ID   A0A6I6IWT7_9RHOB        Unreviewed;       302 AA.
AC   A0A6I6IWT7;
DT   12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT   12-AUG-2020, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Dihydrodipicolinate synthase family protein {ECO:0000313|EMBL:QGX97098.1};
GN   ORFNames=EI983_01920 {ECO:0000313|EMBL:QGX97098.1};
OS   Roseovarius faecimaris.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseovarius.
OX   NCBI_TaxID=2494550 {ECO:0000313|EMBL:QGX97098.1, ECO:0000313|Proteomes:UP000428330};
RN   [1] {ECO:0000313|Proteomes:UP000428330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MME-070 {ECO:0000313|Proteomes:UP000428330};
RA   Nam Y.-D., Kang J., Chung W.-H., Park Y.S.;
RT   "Complete genome sequence of Roseovarius sp. MME-070.";
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
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DR   EMBL; CP034348; QGX97098.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A6I6IWT7; -.
DR   KEGG; rom:EI983_01920; -.
DR   OrthoDB; 9782828at2; -.
DR   Proteomes; UP000428330; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128:SF73; 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE; 1.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW   Reference proteome {ECO:0000313|Proteomes:UP000428330}.
FT   ACT_SITE        134
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   ACT_SITE        162
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   BINDING         46
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
FT   BINDING         203
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ   SEQUENCE   302 AA;  33098 MW;  B15428BC03AA5A17 CRC64;
     MQFEGIWTPI VTPVHEDFSV NEEALAETVE HLIEGGVHGI ISAGTTGEYY AQDFETRAFL
     ARRIKDLIKG RVPYCVGTGA LRTEDSIAYA RMAKEVGADA ILVATPPYSV PTGREIALHA
     LAIDRAVDMP VMLYNYPGRM GVNMDEDTLD RLGRSPNFCG IKESSGDINR LHMIARDYPH
     LGLLCGMDDQ ALEFFAWGAR GWVCAGSNFA PQAHVALYRA CVLEGDFTKG RAIMSAMMPL
     MRVLEQGGKF IQCIKHGLTL RGINAGPPLR PLHPLNKDDK RALEEVIRTL DTAIAAIEGE
     GK
//