ID A0A6I8PDE5_ORNAN Unreviewed; 1093 AA.
AC A0A6I8PDE5;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=TATA element modulatory factor 1 {ECO:0000313|Ensembl:ENSOANP00000050198.1};
GN Name=TMF1 {ECO:0000313|Ensembl:ENSOANP00000050198.1};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000050198.1, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000050198.1, ECO:0000313|Proteomes:UP000002279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000050198.1,
RC ECO:0000313|Proteomes:UP000002279};
RX PubMed=18464734; DOI=10.1038/nature06936;
RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., Ponting C.P.,
RA Grutzner F., Belov K., Miller W., Clarke L., Chinwalla A.T., Yang S.P.,
RA Heger A., Locke D.P., Miethke P., Waters P.D., Veyrunes F., Fulton L.,
RA Fulton B., Graves T., Wallis J., Puente X.S., Lopez-Otin C., Ordonez G.R.,
RA Eichler E.E., Chen L., Cheng Z., Deakin J.E., Alsop A., Thompson K.,
RA Kirby P., Papenfuss A.T., Wakefield M.J., Olender T., Lancet D.,
RA Huttley G.A., Smit A.F., Pask A., Temple-Smith P., Batzer M.A.,
RA Walker J.A., Konkel M.K., Harris R.S., Whittington C.M., Wong E.S.,
RA Gemmell N.J., Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J.,
RA Zemann A., Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., Taylor J.,
RA Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., Huang X., Stark A.,
RA Kheradpour P., Kellis M., Flicek P., Chen Y., Webber C., Hardison R.,
RA Nelson J., Hallsworth-Pepin K., Delehaunty K., Markovic C., Minx P.,
RA Feng Y., Kremitzki C., Mitreva M., Glasscock J., Wylie T., Wohldmann P.,
RA Thiru P., Nhan M.N., Pohl C.S., Smith S.M., Hou S., Nefedov M.,
RA de Jong P.J., Renfree M.B., Mardis E.R., Wilson R.K.;
RT "Genome analysis of the platypus reveals unique signatures of evolution.";
RL Nature 453:175-183(2008).
RN [2] {ECO:0000313|Ensembl:ENSOANP00000050198.1}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000050198.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A6I8PDE5; -.
DR Ensembl; ENSOANT00000050268.1; ENSOANP00000050198.1; ENSOANG00000000495.3.
DR GeneTree; ENSGT00390000010697; -.
DR Proteomes; UP000002279; Chromosome X1.
DR Bgee; ENSOANG00000000495; Expressed in fibroblast and 8 other cell types or tissues.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR InterPro; IPR022092; TMF_DNA-bd.
DR InterPro; IPR022091; TMF_TATA-bd.
DR PANTHER; PTHR46515:SF1; TATA ELEMENT MODULATORY FACTOR; 1.
DR PANTHER; PTHR46515; TATA ELEMENT MODULATORY FACTOR TMF1; 1.
DR Pfam; PF12329; TMF_DNA_bd; 1.
DR Pfam; PF12325; TMF_TATA_bd; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279}.
FT DOMAIN 978..1087
FT /note="TATA element modulatory factor 1 TATA binding"
FT /evidence="ECO:0000259|Pfam:PF12325"
FT REGION 38..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 196..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 438..757
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 829..895
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 986..1090
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 58..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1093 AA; 122850 MW; 12FBD2FCC838EC0D CRC64;
MSWFNASQLS SFAKQALTQA QKSIDRVLDI QEEEPTAWAE TIPYGEQGKG FPTSRGWDTS
AWGLNSNPEP QSQPVASPKA ITKPVRRILL DESENFFSAF LSPADVQQSS VVSKPPTKSQ
RPKEEVKSNL HESPHSVQPE TCETTVTAVK DSSLQESGEA IPRLKTEMVL EENISEGADI
KVSSLTLEVP EGVVGVKSSG KRGLGSPTES LMPESKNVGV EGKEQKPEDR QSNTPSPPIS
TFSSGTSTTS DIEVLDHESV ISESSASSRQ EAADSKSSLH LMQTSFQLLS ASACPEYNRL
DDFQKLTESC CSSDAFERID SFSVQSLDSR SVSEINSDDE MSGKGYALVP IPVSSSTPRT
ETAESMGRKS EAEVSETLII PPEEAEMEES GRSATPVNSE QPDVLVVTPP INEDSAVVEE
DPVPCRDDES QPEVLFEKED LCKTIDVLNE KLEKRETQLL AVSKEKAFLE EAYDNLKDEM
FRVKEESSSI SSLKDEFTQR IAEAEKKVQV ACKERDAAKK EVKTIKEELA MRLNCNETAE
LLKEKDEQIQ GLMEEGEKLS KQQLHNSNII KKLRAKEKEN ENINAKQSKK KRELEEELQH
LKQVLDGKEE VEKQHRENIK KLNSVVEQQE KDLGRLQANM DELEEKNRSV QAALDSAYKE
LADLHKANAT KDSEAQEAAI SREMKAKEEL YVALEKAQEE ARQQQETLAI QVGDLRLALQ
RTEQAAARKE DYLRHEISEL QQRLQEAENR NQELGQSVTS ATRPLLRQIE NLQATLGTQT
ASWEKLEKNL SDRLGESQTL LAAAVERERA AVEELLSNKI QVSSTESQNS LLRQENSRFQ
AQLEAEKNKF QKLKDENNRC QVELENLKDE YFNALEETRK EKVLLNSQLE MEKMKVEQER
KKAFFAQEMV KEKERKPFPF STMESVSSTP TLSRSSSISG VDMSGLQASV LSQDEVHDHS
LGPMCMSANG SNLYDAIRMG AGSSIIENLQ SQLKLKEGEI IHLQLEIGNL EKTRSIMAEE
LVKLTNQNDE LEEKVKEIPK LRAQLRDLDQ RYNTILQMYG EKAEEAEELR LDLEDVKNMY
KTQIDELLKQ RPN
//
