ID A0A6I8QRC4_XENTR Unreviewed; 157 AA.
AC A0A6I8QRC4;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Lysine (K)-specific demethylase 4B {ECO:0000313|Ensembl:ENSXETP00000070985};
DE SubName: Full=Lysine-specific demethylase 4B isoform X6 {ECO:0000313|RefSeq:XP_031752997.1};
GN Name=kdm4b {ECO:0000313|Ensembl:ENSXETP00000070985,
GN ECO:0000313|RefSeq:XP_031752997.1,
GN ECO:0000313|Xenbase:XB-GENE-1012886};
GN Synonyms=jmjd2b {ECO:0000313|RefSeq:XP_031752997.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000070985};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000070985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000070985};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000070985}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2020) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_031752997.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_031752997.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_031752997.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012813685.1; XM_012958231.2.
DR RefSeq; XP_031752997.1; XM_031897137.1.
DR Ensembl; ENSXETT00000074475; ENSXETP00000070985; ENSXETG00000005352.
DR Xenbase; XB-GENE-1012886; kdm4b.
DR Proteomes; UP000008143; Chromosome 1.
DR Bgee; ENSXETG00000005352; Expressed in brain and 19 other cell types or tissues.
DR GO; GO:0140684; F:histone H3K9me2/H3K9me3 demethylase activity; IEA:UniProtKB-EC.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR003349; JmjN.
DR PANTHER; PTHR10694; LYSINE-SPECIFIC DEMETHYLASE; 1.
DR PANTHER; PTHR10694:SF30; LYSINE-SPECIFIC DEMETHYLASE 4B; 1.
DR Pfam; PF02375; JmjN; 1.
DR SMART; SM00545; JmjN; 1.
DR PROSITE; PS51183; JMJN; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 14..56
FT /note="JmjN"
FT /evidence="ECO:0000259|PROSITE:PS51183"
SQ SEQUENCE 157 AA; 18197 MW; 5FBBE27A332D3883 CRC64;
MASEGTQQNP SCKIMTFRPT LEEFQDFGKY MAYIESQGAH RAGLAKVIPP KEWRPRRTYD
DLDEMVIPAP IQQVVTGQSG LFTQYNIQKK PMTVGEYRRL ANSNKYCTPR HQDFDDLERK
YWKNLTFVSP IYGADISGSL YDSARITTPR LLFWAMQ
//
