ID A0A6I8T7P4_AEDAE Unreviewed; 835 AA.
AC A0A6I8T7P4;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:AAEL005152-PH};
GN Name=5566048 {ECO:0000313|EnsemblMetazoa:AAEL005152-PH};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL005152-PH, ECO:0000313|Proteomes:UP000008820};
RN [1] {ECO:0000313|EnsemblMetazoa:AAEL005152-PH, ECO:0000313|Proteomes:UP000008820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL005152-PH,
RC ECO:0000313|Proteomes:UP000008820};
RG Aedes aegypti Genome Working Group (AGWG);
RA Matthews B.J.;
RT "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AAEL005152-PH}
RP IDENTIFICATION.
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL005152-PH};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR AlphaFoldDB; A0A6I8T7P4; -.
DR EnsemblMetazoa; AAEL005152-RB; AAEL005152-PB; AAEL005152.
DR EnsemblMetazoa; AAEL005152-RC; AAEL005152-PC; AAEL005152.
DR EnsemblMetazoa; AAEL005152-RD; AAEL005152-PD; AAEL005152.
DR EnsemblMetazoa; AAEL005152-RE; AAEL005152-PE; AAEL005152.
DR EnsemblMetazoa; AAEL005152-RG; AAEL005152-PG; AAEL005152.
DR EnsemblMetazoa; AAEL005152-RH; AAEL005152-PH; AAEL005152.
DR Proteomes; UP000008820; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR InterPro; IPR012934; Znf_AD.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24388:SF54; C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR CRZA; 1.
DR PANTHER; PTHR24388; ZINC FINGER PROTEIN; 1.
DR Pfam; PF07776; zf-AD; 1.
DR Pfam; PF00096; zf-C2H2; 1.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS51915; ZAD; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01263};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 8..79
FT /note="ZAD"
FT /evidence="ECO:0000259|PROSITE:PS51915"
FT DOMAIN 327..355
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 90..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 746..835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..165
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..535
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..781
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..806
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..824
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 10
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 13
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 52
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
FT BINDING 55
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01263"
SQ SEQUENCE 835 AA; 94214 MW; 2CF1EFF173FD8146 CRC64;
MATKLYQRCC RICMDDAKKQ IDVLSDETLV ETLQQLYNVR VDKNDRITKK ICVDCVQEAK
ETQKWLNFYE EQKKLINENQ RIYNEELISQ LGPETTDSPS LSATSTKTGR ASRTRNASRR
IEDDDDEEIK GEKDEDFIPR KSPRMIKKEG VSTRRNIKRE WIPSDGSERG STTTTPTEHE
TDDDEHEEEA SETGTSTSDG ELKCPKCEKV FSEIDQLERH NCEFICNICS ATVKYRHSLK
RHMITVHKIK ASQWEDYWNP TGDLQGDSLL VETSKPKKRY RYESDSPTDM EEDSNTDENE
ADKDLVCNHC GDKFYSTQEM KNHDCDYGCN ICGTKFASRT SVRRHKIRLH NIDPNDPSVA
PRSRATSTTP AASTSRPPSR PPSRAGSENS DDEPLASLAS DDLRYRFFCP SCDYSSYKRS
TITTHLITFH NTRKELIDVQ SIPKKFVPKT STFTRAKTPV PETAPARAKT PTVFESTNRS
KTPSPVESAP IRSKTPEPVK TYRPPSTTPH KAQPQTIATK NHQPVAQIFP TQHRSRSRSI
HQDSQNSSKR KRSYSSCSNK SSRSVRSRSN PPSDRQILTA KRRLSPSRAL TSVHEKFRPT
VTGIQSNRLF VSIRQGCELT QQGQPIRFRA SSYLLQDSCP TKRLFKLRAP VGTERQQVQS
LRGIFNKLSH QISNHSKVNE IDVDSLVLDY IHPPAVTKVD DPLDKTSFEI RELDSDEPAQ
LVVVETPIPD ETNDDDAEPQ LVIVTEDNGQ TVEVDGGGSA DVNPIEMAAS DREEKGDDGN
GPAVESMDVD DANQETEDTN EETADPIAEA PEEKEPESPD SQQEGHDENV SITPD
//
