ID A0A6I8T9U5_AEDAE Unreviewed; 212 AA.
AC A0A6I8T9U5;
DT 12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT 12-AUG-2020, sequence version 1.
DT 13-SEP-2023, entry version 13.
DE RecName: Full=Synaptosomal-associated protein {ECO:0000256|RuleBase:RU003496};
GN Name=5565055 {ECO:0000313|EnsemblMetazoa:AAEL004559-PD};
OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Aedini; Aedes; Stegomyia.
OX NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL004559-PD, ECO:0000313|Proteomes:UP000008820};
RN [1] {ECO:0000313|EnsemblMetazoa:AAEL004559-PD, ECO:0000313|Proteomes:UP000008820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL004559-PD,
RC ECO:0000313|Proteomes:UP000008820};
RG Aedes aegypti Genome Working Group (AGWG);
RA Matthews B.J.;
RT "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AAEL004559-PD}
RP IDENTIFICATION.
RC STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL004559-PD};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Synapse, synaptosome
CC {ECO:0000256|ARBA:ARBA00034102}.
CC -!- SIMILARITY: Belongs to the SNAP-25 family.
CC {ECO:0000256|ARBA:ARBA00009480, ECO:0000256|RuleBase:RU003496}.
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DR AlphaFoldDB; A0A6I8T9U5; -.
DR EnsemblMetazoa; AAEL004559-RD; AAEL004559-PD; AAEL004559.
DR EnsemblMetazoa; AAEL004559-RH; AAEL004559-PH; AAEL004559.
DR Proteomes; UP000008820; Chromosome 1.
DR GO; GO:0043005; C:neuron projection; IEA:UniProtKB-KW.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR CDD; cd15885; SNARE_SNAP25C; 1.
DR CDD; cd15889; SNARE_SNAP25N_23N; 1.
DR Gene3D; 1.20.5.110; -; 2.
DR InterPro; IPR000928; SNAP-25_dom.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19305; SYNAPTOSOMAL ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR19305:SF14; SYNAPTOSOMAL-ASSOCIATED PROTEIN-RELATED; 1.
DR Pfam; PF00835; SNAP-25; 1.
DR SMART; SM00397; t_SNARE; 2.
DR SUPFAM; SSF58038; SNARE fusion complex; 2.
DR PROSITE; PS50192; T_SNARE; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Synaptosome {ECO:0000256|ARBA:ARBA00022599}.
FT DOMAIN 26..88
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT DOMAIN 148..210
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT COILED 57..91
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 172..199
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 212 AA; 23574 MW; 95B1404F675E9981 CRC64;
MPAAVPAENG GGAPKTELQE LQLKSQQVVD ESLDSTRRML ALCEESTEVG MRTIVMLDEQ
GEQLDRIEEG MDQINADMRE AEKNLSGMEK CCGICVLPCN KSASFKEDDG TWKGNDDGKV
VNNQPQRVMD DRNGLGPQAG YIGRITNDAR EDEMEENMGQ VNTMIGNLRN MALDMGSELE
NQNRQIDRIN RKGESNEDRI KVANEKAHSL LK
//
