ID   A0A6I8TEF0_AEDAE        Unreviewed;      1325 AA.
AC   A0A6I8TEF0;
DT   12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT   12-AUG-2020, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   RecName: Full=Tetratricopeptide repeat protein 21B {ECO:0008006|Google:ProtNLM};
GN   Name=5575834 {ECO:0000313|EnsemblMetazoa:AAEL012104-PB};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL012104-PB, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EnsemblMetazoa:AAEL012104-PB, ECO:0000313|Proteomes:UP000008820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL012104-PB,
RC   ECO:0000313|Proteomes:UP000008820};
RG   Aedes aegypti Genome Working Group (AGWG);
RA   Matthews B.J.;
RT   "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AAEL012104-PB}
RP   IDENTIFICATION.
RC   STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL012104-PB};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TTC21 family.
CC       {ECO:0000256|ARBA:ARBA00010935}.
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DR   EnsemblMetazoa; AAEL012104-RB; AAEL012104-PB; AAEL012104.
DR   InParanoid; A0A6I8TEF0; -.
DR   OrthoDB; 121960at2759; -.
DR   Proteomes; UP000008820; Chromosome 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 5.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR040364; TTC21A/TTC21B.
DR   PANTHER; PTHR14699; STI2 PROTEIN-RELATED; 1.
DR   PANTHER; PTHR14699:SF0; TETRATRICOPEPTIDE REPEAT PROTEIN 21 HOMOLOG; 1.
DR   Pfam; PF13432; TPR_16; 1.
DR   Pfam; PF14559; TPR_19; 1.
DR   Pfam; PF13174; TPR_6; 1.
DR   SMART; SM00028; TPR; 13.
DR   SUPFAM; SSF48452; TPR-like; 5.
DR   PROSITE; PS50005; TPR; 3.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ   SEQUENCE   1325 AA;  151199 MW;  4DD5A505E3D215C5 CRC64;
     MDELDYKSVI LYYGREKLYR TMQRIVLDAT GKYTADTSFR FYNGIALILE GVRLQEGIRE
     LNQLIGDKDL GMAVVLSLLY AHKRCSVIDK EELLSLDSRL KDERKRLTSM SAYYSSLFLF
     LTGKYDKAKE YADKAQRLGP NNPEILTLKG WCELVSHKPR SSFILDLFDK ALEHGKQIDA
     NIGQVRYHQL NNDFEAAITV LNRLSVRYPE LNIPLIEKMR CHLSNWNWEN AVETSTRILN
     LEPTNLEALQ VKILILVAKD GNYTSSLSAL QYLFTTMEKI EPANGDLFMQ TGQLFSRICG
     RNASILSHTY SFVEKAYKLN SSNAKYITEL GYQNVLQKNY KEATKLFKLA SKLDDSSMYA
     LCGLTLCQMM DSGISEQVSQ QIEFLTEIQG EDKIPLLLLM SSKLHHTNHE TAVSMLLQAS
     EIQFKNLNAL SYGLEYLRQF NPDFLIQLVK ELLKHSPAEQ SMDMMSIDSL HPSLRHSANI
     LDSIVKACPG LVEASYLLAR VQYLSGEVGA AAGTLQKILQ EIDSTYSDAH LLIAQIHIQQ
     KSYQRAAQSL EICLSHNFKV RDDPMYHLLL GIVYKNQQRF EDALKSFFIA MGICGINTNG
     SQGKSVANMK SDGKPLGVSD LLTLYLEVIN THVLMNQNSE ALKLMQLVSS EFASTTEEGR
     LSVATADFYM QQGNFVKAIE LLKTIKPNQQ YYIQAKTKMA HFYLVHKKDR LAYAQCFREL
     VANCPGPSSY LMLGDAYMSI QEADEAIEAY RQAQKQNPRD ALLASKLGRA YVKTHQYKKA
     ISYYQEAIAT PENSLLKLDL AELFLKLKQY SNAEQTLVDE IELSKNEIED ISTLQTRTKQ
     LLLLARVREK AGYLNSSLNT LKEARDNQFK ILKHLEMEQN VALHEQNKIL VSRICVLMAE
     QSIAIRDNEQ AIHHYREALR MNSNDVGLLS ALARTYMHVN NMDQCQLTCA TILQNDPNNE
     VASVMMADLS FRRMDFENAA FHFSQLLLSQ STYWTALARL IEVMRRSGTL HDVQQFLHRA
     EDECARPDTE AGLNYCKGLN EWYGGNPNSA LRFFNNCRKD TEWGQQAIYN MIEICLNPDG
     DLPNEGVIDI GADDLEIKDS RAMALRTAER LLKELKPRPG VIDNEALNHR LLENFLLVAS
     RQKHSIDRAL QDFTAIATQE EYKDHVGAIY GMASAYVILK QSQRAKNQLK RIVKVNWTFE
     EADYLEKSWL LLADLYLQAG KYEMSTDLLR RVLEHNKSCT KAYELLGLIS EKEQNFRNAS
     MYYDSAWKCS AKSKPNIGYK LAFNYMKIKR YAEAIDICQQ VLKTHPDYPS IKKDILDKCR
     NNLKN
//