ID   A0A6I8TTC0_AEDAE        Unreviewed;      3002 AA.
AC   A0A6I8TTC0;
DT   12-AUG-2020, integrated into UniProtKB/TrEMBL.
DT   12-AUG-2020, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   RecName: Full=Pericentrin/AKAP-450 centrosomal targeting domain-containing protein {ECO:0000259|Pfam:PF10495};
GN   Name=5567941 {ECO:0000313|EnsemblMetazoa:AAEL025762-PH};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EnsemblMetazoa:AAEL025762-PH, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EnsemblMetazoa:AAEL025762-PH, ECO:0000313|Proteomes:UP000008820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL025762-PH,
RC   ECO:0000313|Proteomes:UP000008820};
RG   Aedes aegypti Genome Working Group (AGWG);
RA   Matthews B.J.;
RT   "Aedes aegypti genome working group (AGWG) sequencing and assembly.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AAEL025762-PH}
RP   IDENTIFICATION.
RC   STRAIN=LVP_AGWG {ECO:0000313|EnsemblMetazoa:AAEL025762-PH};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
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DR   EnsemblMetazoa; AAEL025762-RH; AAEL025762-PH; AAEL025762.
DR   Proteomes; UP000008820; Chromosome 3.
DR   GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   InterPro; IPR028745; AKAP9/Pericentrin.
DR   InterPro; IPR019528; PACT_domain.
DR   PANTHER; PTHR44981; PERICENTRIN-LIKE PROTEIN, ISOFORM F; 1.
DR   PANTHER; PTHR44981:SF2; PERICENTRIN-LIKE PROTEIN, ISOFORM F; 1.
DR   Pfam; PF10495; PACT_coil_coil; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820}.
FT   DOMAIN          2823..2908
FT                   /note="Pericentrin/AKAP-450 centrosomal targeting"
FT                   /evidence="ECO:0000259|Pfam:PF10495"
SQ   SEQUENCE   3002 AA;  344542 MW;  5DC79839979F9098 CRC64;
     MNIGRLKLKP KGSSTSKSGS PLPPVQVPPN LSQFSSPSNL GPNKSPVVSR SEPSVRFKLE
     EDIIGSLSVS SASASGSNNE DSLEIMEEID IPDDESTQDN DASGSISENL VLSAAPAENV
     PQRSVDNSKI ATDRKKQLFD IDNELPGESG VRKFDIDDLQ LSGDEIAQHF QSFSESTDLK
     DEDNKVNLAV KKKLLKQNHD VGSLGTLLDN IESSSDVLGS DPKKEESDLK QKVGESKKEL
     SPLNEDVVLI NNSKVSLKSL KKLQKQSNVL DNSGDNSYST TNDISELARD TESDRIMSDN
     NDNSSRSDVA SKPMDSDKEA SLQKLSSLML RSRSAEIEEK NVQSEDKPEF ASLGVVKLCN
     EQSSEVHDSS VEEDNSIEEM LMSNASVDIL AVNEMVLSEN QQLKEDSSDS NLSGDLKEKI
     LTSSKSFEEI KSQHELDVPA DNLEGNKPVV VKQMEKVVDI KEALEDISEE SEQTLTNSNH
     SESRPNTDDE QSKPLAVVEK GKEIRKILEE KLLHKQLNIE STIYEDNKEN IPDSLSVNKS
     FDLDSVVSLN MFQAMNNEIK QLHEIIATKD MMLEAYSTRD SLKETRLESL RDPQRSSDSS
     SLATNSTEYR PLNDETVSKK ELLQKVADQN QWIVTLAEKL QEINQAREME RSESIKLVAE
     VNRLTKQLAE NADTIKQRPH WMRDQESTGQ RISEISIDLV SETDDALSDF PDLYEERSNR
     NSRERQLDLN LDIDYSEQNP LHIPTAISKQ LEQFRKYLSA DELRLFNMVQ GKFDDYLQQE
     LDKMKTTSEE ELKIIQERLV SEKNEHDAEV SRLRQLLSNV KSGSVEIEDL KSELEARHTQ
     EMDDLRTYFQ EKVAEFEKQY SEKVLSQHSR QMSNDTASDI SDQEEFPEEN GGYHSKHTSP
     KRKAKEDIYL SPTHRKITPT TIDTTESSAD EVMEFPMEEE DEAHLTVDSL REYYQNKLKE
     LKRQHEQDLR ELRKTFKQFE EKDIDEKGLA LLSDTISEDY HWPPELILLR EKLTAKSQLE
     IAQLQIKHEE EMAKVKADFE KQLQWKLKRQ STFDSARDLD KIISERDNLR ELSSTLRSVL
     CELVRYVSNC EDDLNSTVID ELHKYGIVPG NAEEVLECSA LDMSVSNIST LSTKKFLKFT
     PDVSGLISII EDPTLLEYIS KESVNHDGAN RSLNLDECLE KLRSEAMHIL SLSEKIAKKS
     STKDEDLDKV SVKSDSCEEE DGLKRKVVKK DTVGSRSFDE NIVRHSRTMD ASHIDSSLPM
     DLTALQCSGE LNVQLHELRN EKRQLEMKLA DALSKQNSLV VELNETKQHL LELNSQKVEI
     SEGYGTNALL PCAQKQANSF SELQEKAKQI LASSPDSDID NSTNLLQLVE EFCREGERYM
     ENGKRDKLDL QSQIDAADKQ LKATRQFLED QAAEREQERD EFVKEIEKLK IQLREKDKDK
     TNIDRVTKED GFLCDSCSCG IDNREIIEKL ETAEQNIKEL SAEIAARDDK IRKLENDLKD
     SIDKGFTLRE IITELETQNE SKAIDQHVMV TKIKELESYI DAQNRQNESL HQETDMTVRG
     YDDKIAKLEE ELRQTKPSVE HSLVLEALTV QLRDVEETLE RKTKNLETLH ANSSASLVCS
     SPSEDISVNS PSHRKKSAEN SSIPPLPVDE VQRIFDKLHR HTRVEEVAIK RINDLEMQIC
     SVRNEYAELQ HERDVLQERM SEQSLKITTL QSKLDEQRLR AEELHRQGTS HLTVKVHDLQ
     NEVVNLKETL QTRDKQITSL KNFLENSQQV IERQEKELAM NQADNDRSQY ELKLEAELQA
     KCDEIQQLKN KIQNDMINKL ALPDLMETML ADKNEEIDQL KEKLSQLQSQ HHPPASHLGH
     GKEDDNARTL SDIVSITDCD ESDMVMRRLP EQNEGLLPTQ HSIPMMVWSD FCILSIKETP
     SNFFNLKEQH QTASTIHSTT HLPTSSSNVS PLQHAMQLPK ATLFPLGFEG AFLQDFSAVF
     PRPTPSTGTS SGGTPEFIPR HINFSLIDNP RSAEGKDRLR EPAFIEEIHE QEEEKVMAQT
     MTASGGKRLS DISENVSEED KGKLENELES LKMQLDRITN EKNVALERMH AEIQEKIENI
     EDLQVELAAR NKLYEDLLRE KKDLRDELEK VKHDLDQLES DACNLQKKEN ELKEVLESMT
     HKDQEMCDLK GICNKLREEI EQHVRDSESL KSEQQKNHLL IDTLKQQVES LNKTIGHKDE
     LMSKLEKDIL NYSKNEEKYL EQLKVLDAKE IELRLLQGNY KDRMQEIEML NEDNKFLNED
     ITRLKNEIAK SSSNSSSNPS YVQFLKQNCE KIEEELRETK ALLTEKMLAL ERVKIDLTSC
     QREAEDVKSL LKEKEMIIQQ IGDDGNTLHQ ALSNIQNQMQ ETSGNLNKKL REEQDRNTAL
     LAEIDRLKTL LQRSDNSSSP KPFSVEEIAE QLEKELNYSA QLDSSILKAI ESDDVNSDDE
     ANEAIKKSKD GLADAVQLEE LTQKLRMEAE KGNKLKEMLE AEKHNSNEIQ MQDAEIIEAM
     RLRLEAAIDN EGTLQKLLSE ERSKNERLST LMAGVQRTKS FDNYLLMKNK SPHDSPSRRL
     NRSNEFESEM VARFESEIKF LNAQNERERE RAIDLQRALE RERNRFEKEI ADRNEYGEQV
     KRELMRVTKE KEQLEVELDN EQEKLLLSHK EIESLERRIN ALQEAESMRS LRKDRSLEFQ
     DIRLRLENVE QERVQLLETN RSLRTEVERR KQNEAHLMEA LSRGNSLKES GVPEEFLTKL
     KDLNRMLEAN ARENHQQAET LRLMVEERRA LQQRIQELER FNVNSNRSNR DDLEERANHL
     FGKYLRSESH RKALVHQKRY LQIVLTTYEE NEAKALQLLN AQNVPMGIQG LSFAKPNADE
     NHPRRKSFRS VVTAIIAIER MKFIVRKWQG GRRVCAKAIF SQQFTPRRSQ SATTNVWTRS
     QNSHFVEYNA SPPSRDRAVF HPSVVHQVQN YPSQYLRLPE SQLVMNADLR ERLEDQYNQT
     NR
//