ID A0A6Q2XAJ8_ESOLU Unreviewed; 605 AA.
AC A0A6Q2XAJ8;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Erythrocyte membrane protein band 4.1 like 4A {ECO:0000313|Ensembl:ENSELUP00000050260.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000050260.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000050260.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000050260.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A6Q2XAJ8; -.
DR Ensembl; ENSELUT00000073989.1; ENSELUP00000050260.1; ENSELUG00000004455.2.
DR GeneTree; ENSGT00940000159623; -.
DR Proteomes; UP000265140; LG14.
DR Bgee; ENSELUG00000004455; Expressed in heart and 14 other cell types or tissues.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13186; FERM_C_NBL4_NBL5; 1.
DR CDD; cd17107; FERM_F1_EPB41L4A; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR030696; Band4.1-like4A_FERM_F1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF4; BAND 4.1-LIKE PROTEIN 4A; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 11..299
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 395..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..429
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..474
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..492
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..540
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 69650 MW; 7C8F3D931C173263 CRC64;
MSCFCATQEE FYCEVLLLDE TKLTLTTQQQ GIKKSTKGSV VLDFVFNHVN LAETDYFGLR
YCDRSHQTYW LDPSKTLSEH KDLITTGPPY TLYFGVKFYA EDPCKLKEEI TRYQFFLQVK
QDILQGRIPC PFDVSAQLAA LAIQSELGEY DPYKHVPGYV SEYRFVPDQK EELEDAIERI
HKTLTGQVPS EAEVNYLGIA KTLDMYGVDL HPVFGENQSE YFLGLTPVGV VVYKNKTQVG
KYFWPRITKV HFKESQFELR VVGKDCTETS FFFEAPNKTA CKHLWKCCVE HHTFFRMPEN
DANTLTRKLS KFGSLGSKHR YSGKTAIQMS RDPSISLPRP DQHVVRTHSK TYPKRLLQTT
GHLNKIRQRY GGFFGVCLPI CLPVCFTFSS KLMKAENGGP EEQRGKPSAP WDENAPQSGL
YNTANERTKS PKFPAARGRT PPVGSDNEVQ YQSPRRRKQN QSRSRGNTSS GSESENSTRE
HRKKRNRSRQ ENEMVDSGPQ WEAVLRRQKE RSQNDPNHRR SRHRSRSKEL VDPAPDLTEE
QLKEIPYKKV ETQGDPIKIR HSHSPRSFRQ YRRSQCSEGE RSVLSEVNIA GQITFLTNML
KKHTA
//
