ID A0A6Q2YAN9_ESOLU Unreviewed; 715 AA.
AC A0A6Q2YAN9;
DT 02-DEC-2020, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=NCK interacting protein with SH3 domain {ECO:0000313|Ensembl:ENSELUP00000062471.1};
GN Name=NCKIPSD {ECO:0000313|Ensembl:ENSELUP00000062471.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000062471.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000062471.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000062471.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A6Q2YAN9; -.
DR Ensembl; ENSELUT00000076500.1; ENSELUP00000062471.1; ENSELUG00000007826.2.
DR GeneTree; ENSGT00390000015725; -.
DR Proteomes; UP000265140; LG17.
DR Bgee; ENSELUG00000007826; Expressed in brain and 15 other cell types or tissues.
DR CDD; cd11849; SH3_SPIN90; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR030125; SPIN90/Ldb17.
DR InterPro; IPR018556; SPIN90/Ldb17_LRD.
DR InterPro; IPR035514; SPIN90_SH3.
DR PANTHER; PTHR13357:SF1; NCK-INTERACTING PROTEIN WITH SH3 DOMAIN; 1.
DR PANTHER; PTHR13357; SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF09431; SPIN90_LRD; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..58
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 102..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..250
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..278
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 78893 MW; A412B4E5E0085FBD CRC64;
MYRSLYAFRS AEPNSLHFGA GESFLILERS NKHWWLGSRC SSGETGYVPA SYIERIQAPE
QDEVLQSIDR AIEGIHNVAM KNGGKYNLEQ RDVLQKLIHH RKETLSRRSP TPSGTKQVLP
SSTSELSLSH TPQPPNGISH SLSESTDNVQ GFYQVPPQPR RAAPITPPPP EKQRANRRQG
DCLKSSSLPS PCPALAVGSG LSPSVSSGSL NSSSSHSVVS SDVSLPSVAN TPPPVPSRVK
PPPPDDLPSS APSLQPAQFK KGPAPQPQPQ PTPLPLPPTE DQSETDCTPG SPTHSDSVPG
TTGAELIELV RRNTGLSYEL SRVAVGVVVG HLQTTLPQAS SALEKVLLSL VESKSSALPQ
GQVCHDEQRL EVILSDLARH VDDSQQRSWA LHEDHSLIAC YLEELLKILT DADPEVCKKM
CKANHSEPVL SLVSYYQMEH RVSLRLLLLK VFGAMCSLDS ALISILLNSI LPMELARDLQ
TDTQEHKKMC YTALVLTMIF SMGEQVPYHH YEHLNSNFIQ FLLDVIENGL HSDPTEQLPD
LFVNIILAFN LHHTVPSSNV IMQTVIKKNV KVFSEKILLL LNRGDDPVCV FKHTPPAPHA
VLKFLQDVFT SRESASIFYH TDMMVMIDIA VRCISDLSPG DKLRMEYLSL MHSIMRSTDF
MEHRHRLSDL QGALQRILGE EDDDSGGDTA GATAKQMDKL IVQEIYKEFP QIVQS
//
