ID A0ACN2_STRA7 Unreviewed; 219 AA.
AC A0ACN2;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Putative transcriptional regulator {ECO:0000313|EMBL:CAJ88237.1};
GN ORFNames=SAM23877_7063 {ECO:0000313|EMBL:AKZ60106.1}, SAMR0527
GN {ECO:0000313|EMBL:CAJ88237.1};
OS Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 /
OS NBRC 12836 / NRRL B-2516).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=278992 {ECO:0000313|EMBL:CAJ88237.1};
RN [1] {ECO:0000313|EMBL:CAJ88237.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 23877 {ECO:0000313|EMBL:CAJ88237.1};
RA Barona-Gomez F., Lautru S., Francou F.X., Leblond P., Pernodet J.L.,
RA Challis G.L.;
RT "Multiple biosynthetic and uptake systems mediate siderophore-dependent
RT iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces
RT ambofaciens ATCC 23877.";
RL Microbiology (Mosc.) 152:3355-3366(2006).
RN [2] {ECO:0000313|EMBL:CAJ88237.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 23877 {ECO:0000313|EMBL:CAJ88237.1};
RX PubMed=16956972; DOI=10.1093/molbev/msl108;
RA Choulet F., Aigle B., Gallois A., Mangenot S., Gerbaud C., Truong C.,
RA Francou F.X., Fourrier C., Guerineau M., Decaris B., Barbe V.,
RA Pernodet J.L., Leblond P.;
RT "Evolution of the terminal regions of the Streptomyces linear chromosome.";
RL Mol. Biol. Evol. 23:2361-2369(2006).
RN [3] {ECO:0000313|Proteomes:UP000061018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL
RC B-2516 {ECO:0000313|Proteomes:UP000061018};
RX PubMed=26410452; DOI=10.1016/j.jbiotec.2015.09.020;
RA Thibessard A., Haas D., Gerbaud C., Aigle B., Lautru S., Pernodet J.L.,
RA Leblond P.;
RT "Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
RT spiramycin producer.";
RL J. Biotechnol. 214:117-118(2015).
RN [4] {ECO:0000313|EMBL:AKZ60106.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23877 {ECO:0000313|EMBL:AKZ60106.1};
RA Thibessard A., Haas D., Gerbaud C., Aigle B., Lautru S., Pernodet J.-L.,
RA Leblond P.;
RT "Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
RT spiramycin producer.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP012382; AKZ60106.1; -; Genomic_DNA.
DR EMBL; AM238664; CAJ88237.1; -; Genomic_DNA.
DR RefSeq; WP_053141381.1; NZ_CP012382.1.
DR AlphaFoldDB; A0ACN2; -.
DR KEGG; samb:SAM23877_7063; -.
DR Proteomes; UP000061018; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR039538; BetI_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF226; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1474C; 1.
DR Pfam; PF13977; TetR_C_6; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000061018};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 16..76
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 39..58
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 219 AA; 23582 MW; DD4838796A0B6E74 CRC64;
MSARPQDAPR RPSKGERTRA RILDSAAELF SRSGFNAVSL RDIAAHAGLT HAGVLHHFSG
KESLLTAVLG HRDRMDAQSV FPGITHPGAP EPSPAERLRM LVGLVARNSA TPGLVALYTK
LSAEATDPGH PAHHYFKERY RVLREELTVL VEAVRAGSDR PPAVDPAVVA RQLLALMDGL
QTQWLLEPGA VAMEDLVRDY LVRLGLDPDG GVREAGVSG
//
