ID A0AE12_STRA7 Unreviewed; 402 AA.
AC A0AE12;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Putative enolase/dehydratase {ECO:0000313|EMBL:AKZ59604.1};
DE SubName: Full=Putative starvation sensing mandelate racemase / muconate lactonizing enzyme {ECO:0000313|EMBL:CAJ88720.1};
GN Name=rspA {ECO:0000313|EMBL:AKZ59604.1};
GN ORFNames=SAM23877_6559 {ECO:0000313|EMBL:AKZ59604.1}, SAMR1011
GN {ECO:0000313|EMBL:CAJ88720.1};
OS Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 /
OS NBRC 12836 / NRRL B-2516).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=278992 {ECO:0000313|EMBL:CAJ88720.1};
RN [1] {ECO:0000313|EMBL:CAJ88720.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 23877 {ECO:0000313|EMBL:CAJ88720.1};
RA Barona-Gomez F., Lautru S., Francou F.X., Leblond P., Pernodet J.L.,
RA Challis G.L.;
RT "Multiple biosynthetic and uptake systems mediate siderophore-dependent
RT iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces
RT ambofaciens ATCC 23877.";
RL Microbiology (Mosc.) 152:3355-3366(2006).
RN [2] {ECO:0000313|EMBL:CAJ88720.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 23877 {ECO:0000313|EMBL:CAJ88720.1};
RX PubMed=16956972; DOI=10.1093/molbev/msl108;
RA Choulet F., Aigle B., Gallois A., Mangenot S., Gerbaud C., Truong C.,
RA Francou F.X., Fourrier C., Guerineau M., Decaris B., Barbe V.,
RA Pernodet J.L., Leblond P.;
RT "Evolution of the terminal regions of the Streptomyces linear chromosome.";
RL Mol. Biol. Evol. 23:2361-2369(2006).
RN [3] {ECO:0000313|Proteomes:UP000061018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL
RC B-2516 {ECO:0000313|Proteomes:UP000061018};
RX PubMed=26410452; DOI=10.1016/j.jbiotec.2015.09.020;
RA Thibessard A., Haas D., Gerbaud C., Aigle B., Lautru S., Pernodet J.L.,
RA Leblond P.;
RT "Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
RT spiramycin producer.";
RL J. Biotechnol. 214:117-118(2015).
RN [4] {ECO:0000313|EMBL:AKZ59604.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23877 {ECO:0000313|EMBL:AKZ59604.1};
RA Thibessard A., Haas D., Gerbaud C., Aigle B., Lautru S., Pernodet J.-L.,
RA Leblond P.;
RT "Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
RT spiramycin producer.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP012382; AKZ59604.1; -; Genomic_DNA.
DR EMBL; AM238664; CAJ88720.1; -; Genomic_DNA.
DR RefSeq; WP_053140281.1; NZ_CP012382.1.
DR AlphaFoldDB; A0AE12; -.
DR STRING; 1889.SAM40697_5879; -.
DR KEGG; samb:SAM23877_6559; -.
DR Proteomes; UP000061018; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR CDD; cd03322; RspA; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR034589; D-mannonate_dehydratase-like.
DR InterPro; IPR034593; DgoD-like.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR PANTHER; PTHR48080; D-GALACTONATE DEHYDRATASE-RELATED; 1.
DR PANTHER; PTHR48080:SF6; STARVATION-SENSING PROTEIN RSPA; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SFLD; SFLDG00033; mannonate_dehydratase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00908; MR_MLE_1; 1.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000061018}.
FT DOMAIN 129..257
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 402 AA; 44612 MW; F931AA1E3AF6906B CRC64;
MSRIESVEVF VASPGRTFVT LRITTTDGVT GLGDATLNGR ELAVASYLRD HVVPLLIGRD
PARIEDTWQF LYKGAYWRRG PVTMTAIAAV DTALWDILGK TAGLPVHQLL GGRSRDGVLV
YSHASGTDVP SLLDDVERHL ELGYKAVRAQ AAVPGVGGTY GVRKGRVYEP AASELPDEQP
WDTEAYLDFA PRYLEAVRER FGFGFHLLHD VHHRLSPNEA ARFGRSVEAS RLFWMEDPTP
AENQESFRLI RQHTTTPIAV GEVMNSIWDV QHLITEQLID YVRTTVVHAG GITHLRRIFD
LAALHQVRTG SHGATDLSPV SMAAAVHLDI AVPNFGIQEY MGHADETAEV FRTGVTFADG
MLHPSDEPGL GVEYDEKAAE RFPYQRRYLP VARRLDGSVH DW
//
