ID   A0CC06_PARTE            Unreviewed;       897 AA.
AC   A0CC06;
DT   28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Chromosome undetermined scaffold_166, whole genome shotgun sequence {ECO:0000313|EMBL:CAK68323.1};
GN   ORFNames=GSPATT00037107001 {ECO:0000313|EMBL:CAK68323.1};
OS   Paramecium tetraurelia.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX   NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK68323.1, ECO:0000313|Proteomes:UP000000600};
RN   [1] {ECO:0000313|EMBL:CAK68323.1, ECO:0000313|Proteomes:UP000000600}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK68323.1,
RC   ECO:0000313|Proteomes:UP000000600};
RX   PubMed=17086204; DOI=10.1038/nature05230;
RG   Genoscope;
RA   Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA   Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA   Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA   Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA   Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA   Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA   Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA   Cohen J., Wincker P.;
RT   "Global trends of whole-genome duplications revealed by the ciliate
RT   Paramecium tetraurelia.";
RL   Nature 444:171-178(2006).
CC   -!- SIMILARITY: Belongs to the RNR ribonuclease family.
CC       {ECO:0000256|RuleBase:RU003901}.
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DR   EMBL; CT868059; CAK68323.1; -; Genomic_DNA.
DR   RefSeq; XP_001435720.1; XM_001435683.1.
DR   AlphaFoldDB; A0CC06; -.
DR   STRING; 5888.A0CC06; -.
DR   EnsemblProtists; CAK68323; CAK68323; GSPATT00037107001.
DR   GeneID; 5021509; -.
DR   KEGG; ptm:GSPATT00037107001; -.
DR   eggNOG; KOG2102; Eukaryota.
DR   HOGENOM; CLU_002333_5_0_1; -.
DR   InParanoid; A0CC06; -.
DR   Proteomes; UP000000600; Partially assembled WGS sequence.
DR   GO; GO:0000177; C:cytoplasmic exosome (RNase complex); IBA:GO_Central.
DR   GO; GO:0000176; C:nuclear exosome (RNase complex); IBA:GO_Central.
DR   GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IBA:GO_Central.
DR   GO; GO:0004519; F:endonuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0016075; P:rRNA catabolic process; IBA:GO_Central.
DR   Gene3D; 2.40.50.690; -; 1.
DR   Gene3D; 2.40.50.700; -; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR041505; Dis3_CSD2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR001900; RNase_II/R.
DR   InterPro; IPR022966; RNase_II/R_CS.
DR   PANTHER; PTHR23355:SF35; EXOSOME COMPLEX EXONUCLEASE RRP44; 1.
DR   PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR   Pfam; PF17849; OB_Dis3; 1.
DR   Pfam; PF00773; RNB; 1.
DR   SMART; SM00955; RNB; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR   PROSITE; PS01175; RIBONUCLEASE_II; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000600}.
FT   DOMAIN          442..774
FT                   /note="Ribonuclease II/R"
FT                   /evidence="ECO:0000259|SMART:SM00955"
FT   REGION          275..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   897 AA;  104967 MW;  148431463943F368 CRC64;
     MKVQLNSQPR LNKRLQVMIQ AKEVYLSSDI PCQIRGCAFC NQESDIQLEN PIFMLDNEIL
     EQYIDLIEQS NINNIVVLQS QVAYFRKRQQ QSQYAQQMIN LIESNFSKKI YVYQDEFSIH
     TQNGNPLILL AQWYNSHRQF LKTELDLCLL TQNYQMHQQC KNLNIKCFTI QDYVKLYENN
     DLLDFLGMDE EFEQNQEAIN NQFPYIPVEE CVQQIKQGLL FEGRISIDRN NIKLARIFVK
     QFQLEIKINQ QNRVLHGDRV AVELLSEDQW EQQQKQKEIK FDEDDDDDGN NNTHTNDTSH
     EIMSTSHLQN LFRKVQSQNL VPYGKVVSVL QRTERHFCGH VENNIFVPAD GRYPNFILKH
     SKYDTLQDKK IQVQFVDWPV WSDKPLCKLK KVLGKAGDMY IEGNVILLEH QVEIREFSHQ
     VLACLPIEGD KYRISEQEIK RRMDLRDILV CSIDPVGCKD IDDTLHCRRL ENNLYEVGVH
     IADVSHFVKP DSAIDKEAAH RCTTVYLVDR RTDMLPKLLT ENLCSLVSNV DRLAFSVIWI
     MDDQANIKDV KFGKSVIRSV ASLHYQQAQE MIDNPNDNSQ LTQGIRLLNM LAKKLKQLRT
     DQGALSLASN QVKFSFDDET HNPSDVRMYQ LYDTNSLVEE FMLLANCSVA NQILQRFPSI
     SVLRRHQEPK MKQLKELQIL MNDLGYQFSF DTSKLLSESL DQIQRPNDSF FNKLIRMITT
     RCMNEALYVC TADVDYPELY HYGLAAELYT HFTSPIRRYA DVLVHRLLAA SIDLESLPPS
     MSNKIRMTRI CDKLNMRHRM ARFASRASSD YHTYLFFKNR PQQIDQAIIT GILTDKVTVM
     IPRYVLEGTI DAQIIDRMNI IIQGTRYRIF DYIQVEISVE LHSFHKKIHM KYIKNNN
//