ID A0CGR2_PARTE Unreviewed; 197 AA.
AC A0CGR2;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Chromosome undetermined scaffold_18, whole genome shotgun sequence {ECO:0000313|EMBL:CAK69979.1};
GN ORFNames=GSPATT00007419001 {ECO:0000313|EMBL:CAK69979.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK69979.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK69979.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK69979.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
CC -!- FUNCTION: Plays a fundamental role in microtubule organizing center
CC structure and function. Component of the infraciliary lattice (ICL) and
CC the ciliary basal bodies. {ECO:0000256|ARBA:ARBA00025692}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the centrin family.
CC {ECO:0000256|ARBA:ARBA00005253}.
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DR EMBL; CT868074; CAK69979.1; -; Genomic_DNA.
DR RefSeq; XP_001437376.1; XM_001437339.1.
DR AlphaFoldDB; A0CGR2; -.
DR STRING; 5888.A0CGR2; -.
DR EnsemblProtists; CAK69979; CAK69979; GSPATT00007419001.
DR GeneID; 5023161; -.
DR KEGG; ptm:GSPATT00007419001; -.
DR eggNOG; KOG0028; Eukaryota.
DR HOGENOM; CLU_061288_18_3_1; -.
DR InParanoid; A0CGR2; -.
DR OMA; INERYSE; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23050:SF23; AT22559P; 1.
DR PANTHER; PTHR23050; CALCIUM BINDING PROTEIN; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 4.
DR PROSITE; PS50222; EF_HAND_2; 4.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 51..86
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 87..122
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 123..158
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 159..194
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 197 AA; 22945 MW; CA3E190DE6EEA85B CRC64;
MSSKLSQQQT PQKPIRHPPL QRLKPEQYDE QPQQVNVFDP QKYVKPGLSK EDVIKIKECF
DIFDDDKSGA ISPNELKNAI VALGMEQSIE DIVNMIQDLD QDGSRQVDFE EFLQIFGFQG
SIEDEEVLTD LYKQFDSSKE GKITYEDFKR INELVSERYT DQELREMVQF ADLNNDGALN
WDEFKIVIQK ENSNNKK
//
