ID A0D7A2_PARTE Unreviewed; 3951 AA.
AC A0D7A2;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Chromosome undetermined scaffold_4, whole genome shotgun sequence {ECO:0000313|EMBL:CAK78919.1};
GN ORFNames=GSPATT00001961001 {ECO:0000313|EMBL:CAK78919.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK78919.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK78919.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK78919.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
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DR EMBL; CT868318; CAK78919.1; -; Genomic_DNA.
DR RefSeq; XP_001446316.1; XM_001446279.1.
DR STRING; 5888.A0D7A2; -.
DR EnsemblProtists; CAK78919; CAK78919; GSPATT00001961001.
DR GeneID; 5032101; -.
DR KEGG; ptm:GSPATT00001961001; -.
DR eggNOG; KOG3595; Eukaryota.
DR HOGENOM; CLU_000038_0_0_1; -.
DR InParanoid; A0D7A2; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF1; DYNEIN HEAVY CHAIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600}.
FT DOMAIN 811..1220
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1349..1667
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1819..1941
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 2153..2240
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 2283..2512
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 2526..2875
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 2904..3126
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 3363..3476
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 3508..3644
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 3652..3947
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT COILED 2752..2821
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 3951 AA; 462818 MW; 8001B9371A4FFCD7 CRC64;
MSGSPQVRKL NFGPLVKIKK QINLPKIRKQ EESFQAALNI SDYDPQSARD RSFNNRSFRK
LVHTTNINLS TDKKISEEYA VYGLSKLKIE RKEQPFQSER TIKHLYYTQQ DENTNRDWFE
ICLRQPPPHA QAQFYKQSEK QYEWCDVQIL DYNEESEKFL IQQYPKGPKK QVDRLQIKFN
NQNQQFFESM IQQEQLQLHE KQTELAYVNK VMAVDSKLVN SISDKLKQKL LIRFQKYKNQ
NLVTNLIAQV EDMYHQNMKK CVYLKDLTKY KQKFAPIPRM KIFYTSQQQL KKSLMFVNKA
VIDCWLQMIR FMNNFQVNLF EFDKVHLPVS WEKFEQLIDA NMNKIEQQLK KQRFFIYAQI
QENLQNTFNF FNITMPEYVA SDLKSVVQRF DLHYTEYLYK LLRDEQQKII RFYQKFQLVQ
QNIRLVATSL FQLRIVGMNK SKLEKYEQTR NSINDDLELI TLDTSLSQVI NIATYPNRSL
FNIISQLYKI ESEIVPLLKI PQQYSIEREN LAFFEVLKQE TADLIEKEYS KCQQFCKKFL
PYQYLLIPMK TKAINKIFGI EGKEKPTLHQ IRLSVIREAL DNLSKAQREI NYNFIDTQVI
GLFTLNSKEI KQILIQRAQE NYQLIVQKLI EIIKHNVTNI KTHYQEMYAK TSTVPQTEED
LIELKLFLDE IKIQFSKQFL EISQIKKFIN YLDEIFQEYD LMLMKEYYYL LQWPKEIKRS
IKTNSRQIES IERQFFQKLE HDKVEFTEKL FQMKEQFTKI KGFNQFGIVK QQANEMKILA
DWIFQGQEQI NSFNQRETMF QIPLSQYREF HQLVTEFKPF QYLWELANEY EFQKESWLYG
SFKNLNHQQI LQKLTYYVNE TMVLSNTFKE ITDENGQSVT RGFRRALDAF KDNLWVVETL
AIEAFTKKPV LWRELFKECR IQNFDPKEDF SLQSLIQRGI LNVKEQVVQL SQKVEKGWNI
EKRLNEMYDK LVIIEIELQE FRETFIQKNY EEVQTLLDEQ LNVLSMLKSQ QHIKMVLGKA
NQLEYKIVLI QDTLELGMKC QKHWMYLDPI FASEDIKRKL VEETEYFKLV DQSYRQQMAI
LNKNKILWDS IDNEKIKQEF QNNVQLLDSI QKSLSKYLEQ KRTLFPRFYF VSDEELIEIL
ALVKDPNLLQ KHIFKCFEGM HELKFEGNHS LLGMMSSQQE LVIFDKKIEL LKGEKQGNVE
QWLCELQRIM VQTLRTQLNK TLQDLNSQKQ DYISKWPTQC ILLADHIKWT RNTESAIREL
QKMNLHIHLE ILTKQLQETV QLVRNEERMV MKTTLEAMVV MEVHCKDIVQ QLIHQDVKSI
YDFAWVSQLR YYFEDEGVNV RMVNAQIQYG FEYLGKVTRL VITSLTDRCQ RTLLSAMHLN
YGGAPEGPAG TGKSETVKDL AKAVAMPCIV FNCSDGLNYI AMGKFFKGLS SSGAWCCFDE
FNRIDPEVLS VVAQQIFTIQ KAIKEKKNRF TFEGEEINLI PTCAINVTMN PGYAGRSELP
DNLKILFRPC AMMVPDYAMI AEIYLYSIGF EKARELSPKI VTCLKLCNEQ LSPQEHYDFG
MRVLKAVLST AKQLSTGSEE VICLTALINV NKPKFTQSDV QLFLAITQDL FPSINPLNQT
SQILVDYCCE NNYQPDIDFQ EKCQQLHNTI SVRNGVMCIG KTFSGKTAAI STLGKSLGAQ
TLKLNPKAVT TDQLYGKLDP DTKQWSDGIL PILIRENLNK PTKIWIWFDG PVDSLWIENL
NTVLDDNKKL CLTSGEILKI PQTMCMLFEV EDLSAASPAT ISRCGMVYFL QIDWYLQVQS
IQLPGGLEKQ YFIRRMRFLI DHSYAWVKEY VQFPVYDTIN LMVQSFISLL VQLLKSLSEN
QQNSNNWDSC LIFALVWSIG GCLEEKGRSL FNDFLHKLFR TNKSGLKTNF GDDLELKLNF
PEKIEFFSCV FQDGLWIKWT DQQLTEKFEV QPGMQFHEII IPTAELMRND YFCKMGLHFL
FCGPTSTGKS LSMNKFSKFQ ITCSGQTTSN SLQRLIETKI NKRRRKGYYG AEEGHIMIFV
DDLNMPFREP QGAQPAIELL RQWMDQGGWY DLENKEFKYM CDITFLSAMQ PASGGRDQVS
KRYLRYFNLL YIGGFDNQSI SNILQVFVEW VFQKIQPSQD ILKMKNDIVF HTIQVYDKIQ
LSLLPTPAKS LYIYNLRDLI KVFEGMSKVA RINNQYNLVK LWTHECLRVF SDRLIDSYDL
KIFENVLKES TTQIGYQIQD YKNLIYVSFL HNAYDDAGNV VNVKIKLQQV LEEYNQMNQQ
HALSLILFNN AVLHISRIAR ILLAIQGHAL LVGMGGTGRT SLSKLANYII FGEHVQTVDP
RQWDDQLLGI LKHIGLDDHK STIIFNDSQF QTESMLEDVC NIMSHGEVPH LFPPEERIKI
QEEMTYPKFV LNCKLNTHVI LCMQPVGTQF RKRLRMFPTI INCSTIDWFM SWPDEALEST
ASQFLPQNLV KIAVDIHHKV LEIKERFTQE LRRHFYVTPT QYLQLLATFK KIHTEKNENS
RISIDKFETG VEKIIQTEKE VDKIRKVLFE LQPKLEKATV ENLELLKNIQ KKQQEADQTR
LICEFDEQQC SLKREEANQL KDICQKQLDN VLPLLSKATE ALEKITKDDM ILLKSFQKPP
PSAAVVMQGL CYAFQEDEKV KGKNNGKEPP QMEDFWEYSK KYVLNEKLIK RIKKMKIEEI
RAIHPTKIQK LSVFIQNPLF EREKVFNASM AAGNLADWIR AVYSTYEAVE IIEPKKAQLV
EAEKNLKLAE EQVEIKRQAL AEAMLVLSVL SVEYQKARKE KEEIEKKVSQ IQAQLNRAEK
LTNGLGEEKQ RWKRKVIAYK SEQSNADGDC LISAAIISYL GVFPIQYREQ CLQFWKLKLK
QNQVNFSDDY SLQAQLCDPI QINKWIQQKL PNDSFSIDNA IILKQSTRWP LMIDPQLQAN
EWIKNMEDIK VLLILNSTQP PQQVQLQLEH AIQIGYPVLL ENLGQSIDPL YEPILQQKII
RKQNKCSIKF GEKLIEYSND FRFYMTTKLN NPHFQPQVCV MVNMLMFQVT QEGLVDQLLN
IVVKIDEPQK EEQRIKNIQS NFINKNKLIQ TETLILKLLS ESKGELLENE DLIQTLQKSK
DESLSIEEKL KGLEYDRVNF NQIRQFYKPA AEKVASLYFI LNDLAVIEHT YLWSLDFYFS
LYTKSIKEAQ YEKSKRNQNI IEKFILTLYT QINRSLLEKD KLIFRFLLCV KMMNVPTDLI
RATVMGCTLT STDIQIPKGF PWLTSKMWLE LVDLTIQFPQ IFETICSEFV EQKTFWDSFY
QSQTCYKMQY KELDQYQVNM LIKIIKPEQF IQATNEMIRK QIGSAFLENI PTTFEQFYLK
SDNKIPLLCL ITPGADPRQE IIKLASKYEF EDKFNQISLG QGQSQLAIKM ILSAMSQGSW
VLLQNCHLAS SFMPDLEQLF ETQYKKEINA DFRLWLTSQP TSILPHNVIL KSLKITYELP
RGLKNNMLRS YQTLEADKFE QCKKLKEWKN LFFSLSLLHA CLLERKKYGP LGWNIGYNFS
QHDLEISKEQ ILFFLDQYSE IPWDALHYLI AENNYGGRVT DPMDRKLLKI YVEDLVNQKT
ISQDYIFYDI YQTPPQMNLK GYIDHISQLP LNDPPQLFGL HANAEIYSAI LETENLSSVI
LQLLPRTQGD SAQKHTDSLV CKKSQEILKN LPSQFNIDEV QQLFPLTLDN PLNAVIQQEI
TKYNRLLAKI QDSLSVLVQG LDGFINISDQ SLEIYNSVFD NKIPEQWLAL SYLTTKSLGS
WVTDLKQRIE FLNKWITKGQ PRVFWLGGLF FIQGFLTAIL QQYSRKSKIP IDQLRFDFKF
HQDEPSVSGN EVYANGISID GASFDFQEST LTEPSSSILF YPCPIIQFCP TQEIVKTYKY
YSCPLYNTSQ RKGVLTSNGL SVNFICKIKV PINNNKEHWS KRGVALIIQA N
//
