ID A0DAW7_PARTE Unreviewed; 256 AA.
AC A0DAW7;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=GDT1 family protein {ECO:0000256|RuleBase:RU365102};
GN ORFNames=GSPATT00015091001 {ECO:0000313|EMBL:CAK80184.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK80184.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK80184.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK80184.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU365102}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365102}.
CC -!- SIMILARITY: Belongs to the GDT1 family. {ECO:0000256|ARBA:ARBA00009190,
CC ECO:0000256|RuleBase:RU365102}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU365102}.
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DR EMBL; CT868352; CAK80184.1; -; Genomic_DNA.
DR RefSeq; XP_001447581.1; XM_001447544.1.
DR AlphaFoldDB; A0DAW7; -.
DR STRING; 5888.A0DAW7; -.
DR EnsemblProtists; CAK80184; CAK80184; GSPATT00015091001.
DR GeneID; 5033366; -.
DR KEGG; ptm:GSPATT00015091001; -.
DR eggNOG; KOG2881; Eukaryota.
DR HOGENOM; CLU_040186_0_2_1; -.
DR InParanoid; A0DAW7; -.
DR OMA; HRKDYSH; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015085; F:calcium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GO_Central.
DR GO; GO:0032468; P:Golgi calcium ion homeostasis; IBA:GO_Central.
DR GO; GO:0032472; P:Golgi calcium ion transport; IBA:GO_Central.
DR GO; GO:0071421; P:manganese ion transmembrane transport; IBA:GO_Central.
DR InterPro; IPR001727; GDT1-like.
DR InterPro; IPR049555; GDT1-like_CS.
DR PANTHER; PTHR12608:SF1; TRANSMEMBRANE PROTEIN 165; 1.
DR PANTHER; PTHR12608; TRANSMEMBRANE PROTEIN HTP-1 RELATED; 1.
DR Pfam; PF01169; UPF0016; 2.
DR PROSITE; PS01214; UPF0016; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365102};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Signal {ECO:0000256|RuleBase:RU365102};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU365102};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU365102}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT CHAIN 20..256
FT /note="GDT1 family protein"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT /id="PRO_5002623873"
FT TRANSMEM 60..84
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 197..219
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
SQ SEQUENCE 256 AA; 28078 MW; 600D96EC698C456E CRC64;
MSLSLRTFIL ICLIFVGYCK ESGEKHLTIL TQSIGSMLVS EIGDKTFFLA AILSMKFNRV
AVFAGAGGAL VLMTAISCAF GIIVPSLLPR FYTAIVVTII FYFFGAKLLY EWYHMENEGD
KEELKQVEME LEELDKKLLS SHKIIDPENP SEAQKTNLAA VVPLQQIVWQ AFIMTFLGEW
GDRSQITTIS LAAVQDADIV FLGCSLGHLI CTTIAVIGGK LLAHSISEKT VNLAGGIVFI
VFGLMHTYAL ITGDLD
//
