ID A0DC20_PARTE Unreviewed; 220 AA.
AC A0DC20;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Ribosome assembly factor mrt4 {ECO:0000256|RuleBase:RU364039};
GN ORFNames=GSPATT00015464001 {ECO:0000313|EMBL:CAK80587.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK80587.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK80587.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK80587.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
CC -!- FUNCTION: Component of the ribosome assembly machinery. Nuclear paralog
CC of the ribosomal protein P0, it binds pre-60S subunits at an early
CC stage of assembly in the nucleolus, and is replaced by P0 in
CC cytoplasmic pre-60S subunits and mature 80S ribosomes.
CC {ECO:0000256|ARBA:ARBA00004046, ECO:0000256|RuleBase:RU364039}.
CC -!- SUBUNIT: Associates with the pre-60S ribosomal particle.
CC {ECO:0000256|RuleBase:RU364039}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU364039}.
CC Nucleus, nucleolus {ECO:0000256|RuleBase:RU364039}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC {ECO:0000256|ARBA:ARBA00008889, ECO:0000256|RuleBase:RU364039}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CT868374; CAK80587.1; -; Genomic_DNA.
DR RefSeq; XP_001447984.1; XM_001447947.1.
DR AlphaFoldDB; A0DC20; -.
DR STRING; 5888.A0DC20; -.
DR EnsemblProtists; CAK80587; CAK80587; GSPATT00015464001.
DR GeneID; 5033769; -.
DR KEGG; ptm:GSPATT00015464001; -.
DR eggNOG; KOG0816; Eukaryota.
DR HOGENOM; CLU_071690_3_0_1; -.
DR InParanoid; A0DC20; -.
DR OMA; FTEYTEM; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IBA:GO_Central.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR CDD; cd05796; Ribosomal_P0_like; 1.
DR Gene3D; 3.30.70.1730; -; 1.
DR Gene3D; 3.90.105.20; -; 1.
DR InterPro; IPR033867; Mrt4.
DR InterPro; IPR001790; Ribosomal_uL10.
DR InterPro; IPR040637; Ribosomal_uL10-like_insert.
DR InterPro; IPR043164; Ribosomal_uL10-like_insert_sf.
DR InterPro; IPR043141; Ribosomal_uL10-like_sf.
DR PANTHER; PTHR45841:SF1; MRNA TURNOVER PROTEIN 4 HOMOLOG; 1.
DR PANTHER; PTHR45841; MRNA TURNOVER PROTEIN 4 MRTO4; 1.
DR Pfam; PF00466; Ribosomal_L10; 1.
DR Pfam; PF17777; RL10P_insert; 1.
DR SUPFAM; SSF160369; Ribosomal protein L10-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU364039};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364039};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU364039}.
FT DOMAIN 126..197
FT /note="Large ribosomal subunit protein uL10-like insertion"
FT /evidence="ECO:0000259|Pfam:PF17777"
SQ SEQUENCE 220 AA; 25220 MW; F8419DEE3235E35C CRC64;
MPITKRKRTQ VLTKTKKKTP EKKELLVKKL KQSLKKYQRA IIFQYKNLST NPLKEIQQAW
KSDSKLFIGK NKVMQVGLGK GEEQSATKNS YLLSPFLKGE TGLLLTNKTL QEIQEYCDTY
KIPEFARAGH ISDQTIVLKE GIDTLKGFAH SIEPYLRKLG LNTQLINQQI VLNEKFILAQ
EGKPLTVEQT KILRLMNQKL AYLEIAPLCV LEKNGTFKKL
//
