ID A0DDH5_PARTE Unreviewed; 408 AA.
AC A0DDH5;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE SubName: Full=Chromosome undetermined scaffold_46, whole genome shotgun sequence {ECO:0000313|EMBL:CAK81092.1};
GN ORFNames=GSPATT00015952001 {ECO:0000313|EMBL:CAK81092.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK81092.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK81092.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK81092.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600183-50};
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DR EMBL; CT868385; CAK81092.1; -; Genomic_DNA.
DR RefSeq; XP_001448489.1; XM_001448452.1.
DR AlphaFoldDB; A0DDH5; -.
DR STRING; 5888.A0DDH5; -.
DR EnsemblProtists; CAK81092; CAK81092; GSPATT00015952001.
DR GeneID; 5034274; -.
DR KEGG; ptm:GSPATT00015952001; -.
DR eggNOG; KOG0622; Eukaryota.
DR HOGENOM; CLU_026444_0_2_1; -.
DR InParanoid; A0DDH5; -.
DR OMA; HGNAKSP; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0008836; F:diaminopimelate decarboxylase activity; IBA:GO_Central.
DR GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IBA:GO_Central.
DR CDD; cd06828; PLPDE_III_DapDC; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR HAMAP; MF_02120; LysA; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR002986; DAP_deCOOHase_LysA.
DR InterPro; IPR022643; De-COase2_C.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR022653; De-COase2_pyr-phos_BS.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR NCBIfam; TIGR01048; lysA; 1.
DR PANTHER; PTHR43727; DIAMINOPIMELATE DECARBOXYLASE; 1.
DR PANTHER; PTHR43727:SF2; DIAMINOPIMELATE DECARBOXYLASE 1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR PRINTS; PR01181; DAPDCRBXLASE.
DR PRINTS; PR01179; ODADCRBXLASE.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS00878; ODR_DC_2_1; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR600183-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600}.
FT DOMAIN 31..275
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT DOMAIN 276..363
FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00278"
FT ACT_SITE 337
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
FT MOD_RES 57
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
SQ SEQUENCE 408 AA; 45980 MW; 679D08FE64BF77DB CRC64;
MDSNFTIQNL TPKSLVQEFG SPLYVYDEEI IKRQCQTITT ALKNSFDQGA KVLYACKANT
NPNVLKIMKS NGVHGIDAVS PNEVEVALQA GFLNNQITFT ANYMTKEEID YAIQKGVILN
VGEIDTLKKL IAHKAEVIIR LNLDVGIGHH NHVNTGGNDS KFGINLMWKE QLSEIQKQGV
KIIGLHQHMG SKIMKKDHDS YLLGIEKLFQ AATQELELPY LKYIDIGGGF GVKYQDYEET
SDLNLLFSEI KKLYDKYFIN VKPMLFIEPG RYLIAESGYL LCTVQAINTN KSRTFVGTDS
GMHHLIRPAL YESYHEIINS EEKQVESRLV TVCGNICESG DLLGVDRNLK VEVNDVLVIQ
NGGAYGFSMS SNYNLRERPA EILVRDSKPY IIRKRETLDY LLANVVIL
//
