ID A0DDH6_PARTE Unreviewed; 1152 AA.
AC A0DDH6;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Chromosome undetermined scaffold_46, whole genome shotgun sequence {ECO:0000313|EMBL:CAK81093.1};
GN ORFNames=GSPATT00015953001 {ECO:0000313|EMBL:CAK81093.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK81093.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK81093.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK81093.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
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DR EMBL; CT868385; CAK81093.1; -; Genomic_DNA.
DR RefSeq; XP_001448490.1; XM_001448453.1.
DR AlphaFoldDB; A0DDH6; -.
DR STRING; 5888.A0DDH6; -.
DR EnsemblProtists; CAK81093; CAK81093; GSPATT00015953001.
DR GeneID; 5034275; -.
DR KEGG; ptm:GSPATT00015953001; -.
DR eggNOG; KOG0203; Eukaryota.
DR HOGENOM; CLU_002360_4_1_1; -.
DR InParanoid; A0DDH6; -.
DR OMA; MMWPCAM; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0005391; F:P-type sodium:potassium-exchanging transporter activity; IBA:GO_Central.
DR GO; GO:0030007; P:intracellular potassium ion homeostasis; IBA:GO_Central.
DR GO; GO:0006883; P:intracellular sodium ion homeostasis; IBA:GO_Central.
DR GO; GO:1990573; P:potassium ion import across plasma membrane; IBA:GO_Central.
DR GO; GO:1902600; P:proton transmembrane transport; IBA:GO_Central.
DR GO; GO:0036376; P:sodium ion export across plasma membrane; IBA:GO_Central.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 2.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43294:SF22; P-TYPE ATPASE; 1.
DR PANTHER; PTHR43294; SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00121; NAKATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 108..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 829..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 856..878
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1072..1094
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1106..1125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..125
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
SQ SEQUENCE 1152 AA; 129492 MW; D9C8E6A6DC0FF23F CRC64;
MQLLEAQREF DDMTKEIMLR RKKLMQQFEK GKKKVPEKTD ASKAEKFKNM DEHSIPLTEL
EKRLETSVKN GLSKSQIDAK LQLHGKNVLS SREKTPWYMK LLHELTNVFA LLIWAGALLC
FIAYGLSPDD PSNLYLGIVL IVVVVVTAVI TFFQNQKSEA IMEAFKNFIP PETLVIRDGE
QQKLQATELV PGDVVVVEFG KRIPADIRVI ESNEMKVDNS SLTGESMLLL RTPECSHPQN
PLETKNLAFF GTLCKEGNGK GIVLFTGDKT VIGQIAGLVE SSESDETPLK KELNAFITYI
AYIAISIGVV FFVLGFAVGY PAVTNLIFAI GIIVANVPEG LLATVVVALT LTAKKLAGLK
VLVKNLEGVE TLGSTSCVCS DKTGTLTQNK MTVENIWYNG KKLRGHSREK MGPDFKYEYD
LKDPGFQLLH ETAIICSEAV FDSSLPQEQQ IKIQNLIGLT QEQKDVKMEE AKAKWKAAYD
KLPCQEKPTV GDASETALIK FFQPIKDILQ TRNSRNVARD HNMKQARKPF NSTNKYAFII
VEYETENSHY CLLTKGAPER IWGLCDTVYN NGKVEVKDDK WEKGFDQVNA QFGKQGERVL
GFARLHLPKE QFPLGYHFNL DKMNFPFSKQ VFVGLISLID PPKDNVPHAV QKCKSAGIQV
IMVTGDQPVT AAAIARQCNI ITEKTVNEIM EEKNISFEEA FHQSNALVIH GDRLTKMAID
DEGLPEDEKG RQLQEWLSKP QLVFARTSPA QKLIIVAGCQ RRGHIVAVTG DGVNDSPAIK
KADIGIAMGI TGSDVAKDAA DMILLNDDFS SIVVGIEEGR KIFDNFKKCI VYCLTSNIAE
LVPFLGFIIF RLPLPLTTVL VLCIEVGTDV FPSMVFVFED ADLDVMTRRP RTKNEHLVGG
QLLWFAYTQN GILETFCGFF QWYVTLNDFG FTPTTLYFIS NKQGVLPKAD DIYDPNDPWF
GNSNLKENYK DGTCTGTDLD GYEDIDWVYA NHGKYDLRMA YLKCEDGKIV TNIEFGDCHV
DLVSPVTKKP YCYHTEASSY AQTSFFFAVV AGQICNYQAL RQLKSAGFFT GFHNYFMILA
YFVEFLLTWS LAYLEAFNTV FGTRDIIFIH YGICALPYGM VMIIWNEGRK FCIRHFKSKT
ALPSWWDRCV VY
//
