ID A0E9G8_PARTE Unreviewed; 92 AA.
AC A0E9G8;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Cyclin-dependent kinases regulatory subunit {ECO:0000256|RuleBase:RU311113};
GN ORFNames=GSPATT00024666001 {ECO:0000313|EMBL:CAK91935.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK91935.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK91935.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK91935.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
CC -!- FUNCTION: Binds to the catalytic subunit of the cyclin dependent
CC kinases and is essential for their biological function.
CC {ECO:0000256|RuleBase:RU311113}.
CC -!- SIMILARITY: Belongs to the CKS family. {ECO:0000256|ARBA:ARBA00007782,
CC ECO:0000256|RuleBase:RU311113}.
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DR EMBL; CT868665; CAK91935.1; -; Genomic_DNA.
DR RefSeq; XP_001459332.1; XM_001459295.1.
DR AlphaFoldDB; A0E9G8; -.
DR STRING; 5888.A0E9G8; -.
DR EnsemblProtists; CAK91935; CAK91935; GSPATT00024666001.
DR GeneID; 5045117; -.
DR KEGG; ptm:GSPATT00024666001; -.
DR eggNOG; KOG3484; Eukaryota.
DR HOGENOM; CLU_140546_1_1_1; -.
DR InParanoid; A0E9G8; -.
DR OMA; MHEPEPH; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0061575; F:cyclin-dependent protein serine/threonine kinase activator activity; IBA:GO_Central.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0019901; F:protein kinase binding; IBA:GO_Central.
DR GO; GO:0043130; F:ubiquitin binding; IBA:GO_Central.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0007346; P:regulation of mitotic cell cycle; IBA:GO_Central.
DR Gene3D; 3.30.170.10; Cyclin-dependent kinase, regulatory subunit; 1.
DR InterPro; IPR000789; Cyclin-dep_kinase_reg-sub.
DR InterPro; IPR036858; Cyclin-dep_kinase_reg-sub_sf.
DR PANTHER; PTHR23415:SF29; CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23415; CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7; 1.
DR Pfam; PF01111; CKS; 1.
DR PRINTS; PR00296; CYCLINKINASE.
DR SMART; SM01084; CKS; 1.
DR SUPFAM; SSF55637; Cell cycle regulatory proteins; 1.
DR PROSITE; PS00944; CKS_1; 1.
DR PROSITE; PS00945; CKS_2; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|RuleBase:RU311113};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|RuleBase:RU311113};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600}.
FT REGION 71..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 92 AA; 11026 MW; 9BDBCA0519FD9438 CRC64;
MPHYPEDIEY SDKYQDEFYE YRHVILPKHV FKKLTKGKLL NEMEWRGLGV QQSRGWVHYE
CHRPEPHILL FRRPKGTDPN TGLPPQGFSA PY
//
