ID A0ECJ4_PARTE Unreviewed; 520 AA.
AC A0ECJ4;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Chromosome undetermined scaffold_9, whole genome shotgun sequence {ECO:0000313|EMBL:CAK93011.1};
GN ORFNames=GSPATT00003880001 {ECO:0000313|EMBL:CAK93011.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK93011.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK93011.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK93011.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR EMBL; CT868671; CAK93011.1; -; Genomic_DNA.
DR RefSeq; XP_001460408.1; XM_001460371.1.
DR AlphaFoldDB; A0ECJ4; -.
DR STRING; 5888.A0ECJ4; -.
DR EnsemblProtists; CAK93011; CAK93011; GSPATT00003880001.
DR GeneID; 5046193; -.
DR KEGG; ptm:GSPATT00003880001; -.
DR eggNOG; KOG0305; Eukaryota.
DR HOGENOM; CLU_014831_4_2_1; -.
DR InParanoid; A0ECJ4; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IBA:GO_Central.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IBA:GO_Central.
DR GO; GO:1990757; F:ubiquitin ligase activator activity; IBA:GO_Central.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR GO; GO:1905786; P:positive regulation of anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF1; FIZZY-RELATED PROTEIN HOMOLOG; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF117289; Nucleoporin domain; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 249..310
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 337..370
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 467..499
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 65..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 520 AA; 59424 MW; CBF594D6CBC602DD CRC64;
MSTNTVKMLQ QRNNDIEVSC FEDKLQISPS KQNKENSHLS KSKTCDMSDL VRLLHKVDIQ
GVQQGDQIEQ EQDSTPKKQV QQGKTCRYIP LRSGQKQNLN EEFQYREIEE ENQEPQKGSD
YKDQGNVTLK DIYKMHVFGQ PLQSEQLQWE SKNLLHFADN TPSKRKILSD INPAVLETYQ
NLMDYREQYQ NSQDYQFSQR KISKVPFKVL DAPQLQDDFY LNLIDWSSQN VLSVALSSCV
YLWSAYNNRV TKFCDFGNND MVCSLIWNPQ GNQLAIGTGS GEVHIYDQEK MKRIQILEGH
SARVGSLAWS GNTLCSGSKD RSIILHDPRQ KKQTGKFEGH KQEVCGLKWS PDEYQLASGG
NDNKLFVWRM GSQIPLAKFN QHQAAVKAIA WSPHRHGLLS SGGGTADRTI RFFNTLTTQQ
LDWIDTGSQV CNLMFSKNVN EFVSTHGYSM NQIVCWKYPA LQKVTTLMGH TSRVLFLAMS
PDGETIVTGA GDETLRFWNA FPRKEQAQPI NTVLLPQMIR
//
