ID A0EFE7_PARTE Unreviewed; 433 AA.
AC A0EFE7;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 24-JAN-2024, entry version 78.
DE SubName: Full=Chromosome undetermined scaffold_93, whole genome shotgun sequence {ECO:0000313|EMBL:CAK94038.1};
GN ORFNames=GSPATT00026361001 {ECO:0000313|EMBL:CAK94038.1};
OS Paramecium tetraurelia.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK94038.1, ECO:0000313|Proteomes:UP000000600};
RN [1] {ECO:0000313|EMBL:CAK94038.1, ECO:0000313|Proteomes:UP000000600}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK94038.1,
RC ECO:0000313|Proteomes:UP000000600};
RX PubMed=17086204; DOI=10.1038/nature05230;
RG Genoscope;
RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA Cohen J., Wincker P.;
RT "Global trends of whole-genome duplications revealed by the ciliate
RT Paramecium tetraurelia.";
RL Nature 444:171-178(2006).
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|PIRNR:PIRNR005992}.
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DR EMBL; CT868675; CAK94038.1; -; Genomic_DNA.
DR RefSeq; XP_001461411.1; XM_001461374.1.
DR AlphaFoldDB; A0EFE7; -.
DR STRING; 5888.A0EFE7; -.
DR EnsemblProtists; CAK94038; CAK94038; GSPATT00026361001.
DR GeneID; 5047196; -.
DR KEGG; ptm:GSPATT00026361001; -.
DR eggNOG; KOG0937; Eukaryota.
DR HOGENOM; CLU_026996_0_0_1; -.
DR InParanoid; A0EFE7; -.
DR OMA; HSRLEIM; -.
DR Proteomes; UP000000600; Partially assembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:UniProtKB-UniRule.
DR GO; GO:0031410; C:cytoplasmic vesicle; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR CDD; cd09250; AP-1_Mu1_Cterm; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR018240; Clathrin_mu_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR PANTHER; PTHR10529:SF262; ADAPTOR PROTEIN COMPLEX 1, MU SUBUNIT; 1.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 1.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00990; CLAT_ADAPTOR_M_1; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|PIRNR:PIRNR005992};
KW Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005992}.
FT DOMAIN 175..431
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
SQ SEQUENCE 433 AA; 50815 MW; 403BF275347F7098 CRC64;
MFGISSIYIL DQKGRVLITR QYRNELPMNI HETFNKKLLE FDEYTQKPVM IDKDGYTYIF
IRHNNLIFMT VCSQNANCLM IFSFLFRLVQ VLQEYFVNVE EESIRDNFVV VYELLDEMLD
NGYPQTTEFK ILKEFIKTES FQLKEKKQPE QTNFNVVALV SNKISWRKEG IKYKKNEVFL
DVIEKLNMLI GQQGNVIKSE IIGQVQVKCM LSGMPELKLG LNDKAFFEAQ GRQSRARAVE
FDDIKFHQCV RLSKFENERV IQFTPPDGDF ELISYRLDIR VKPLFSVDVL IERKSATKIE
FLVKAKSNFK PKSTANNVEI FVPVPDDAEQ PQFRTAHGSV NYMPDKEAMC WSIKQFGGQR
DFMMNAVFHL PTIVSPNRDK FQKMPINITF EIPYFTVSGF QVRYLKIQDK SGYNALPWVR
YITQNGEYQI RMN
//
