ID   A0EGN4_PARTE            Unreviewed;       920 AA.
AC   A0EGN4;
DT   28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Chromosome undetermined scaffold_95, whole genome shotgun sequence {ECO:0000313|EMBL:CAK94475.1};
GN   ORFNames=GSPATT00026799001 {ECO:0000313|EMBL:CAK94475.1};
OS   Paramecium tetraurelia.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX   NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK94475.1, ECO:0000313|Proteomes:UP000000600};
RN   [1] {ECO:0000313|EMBL:CAK94475.1, ECO:0000313|Proteomes:UP000000600}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK94475.1,
RC   ECO:0000313|Proteomes:UP000000600};
RX   PubMed=17086204; DOI=10.1038/nature05230;
RG   Genoscope;
RA   Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA   Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA   Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA   Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA   Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA   Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA   Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA   Cohen J., Wincker P.;
RT   "Global trends of whole-genome duplications revealed by the ciliate
RT   Paramecium tetraurelia.";
RL   Nature 444:171-178(2006).
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DR   EMBL; CT868677; CAK94475.1; -; Genomic_DNA.
DR   RefSeq; XP_001461848.1; XM_001461811.1.
DR   AlphaFoldDB; A0EGN4; -.
DR   STRING; 5888.A0EGN4; -.
DR   EnsemblProtists; CAK94475; CAK94475; GSPATT00026799001.
DR   GeneID; 5047633; -.
DR   KEGG; ptm:GSPATT00026799001; -.
DR   eggNOG; KOG2044; Eukaryota.
DR   HOGENOM; CLU_007812_0_0_1; -.
DR   InParanoid; A0EGN4; -.
DR   Proteomes; UP000000600; Partially assembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0004534; F:5'-3' RNA exonuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IBA:GO_Central.
DR   Gene3D; 1.25.40.1050; -; 1.
DR   Gene3D; 2.30.30.750; -; 1.
DR   InterPro; IPR027073; 5_3_exoribonuclease.
DR   InterPro; IPR041385; SH3_12.
DR   InterPro; IPR041412; Xrn1_helical.
DR   InterPro; IPR047008; XRN1_SH3_sf.
DR   PANTHER; PTHR12341:SF41; 5'-3' EXORIBONUCLEASE 1; 1.
DR   PANTHER; PTHR12341; 5'->3' EXORIBONUCLEASE; 1.
DR   Pfam; PF18129; SH3_12; 1.
DR   Pfam; PF17846; XRN_M; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000600}.
FT   DOMAIN          25..222
FT                   /note="Xrn1 helical"
FT                   /evidence="ECO:0000259|Pfam:PF17846"
FT   DOMAIN          670..734
FT                   /note="5'-3' exoribonuclease 1 SH3-like"
FT                   /evidence="ECO:0000259|Pfam:PF18129"
FT   REGION          859..920
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          272..299
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        868..885
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        886..907
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   920 AA;  107788 MW;  4BBA94D807D6EBFF CRC64;
     MITKEKELID NILKYFSLQE QTEGRKLYYK AKCQITQGEE LDLQKLEDMC INYMEGIYFV
     LQYYFKGVPS WEWYYHYYYA PLCGDIVGVV SQIVQQLSDQ EQPIIFTKDK PYPPFKQLLP
     SILTPENAML LPEPYGKLLT DKENSILRTP IDYYPESFET DSYGTMYEHQ HITKIPFLDC
     NLVEQAYNSI PDTHDSRNEQ ALSIFYQYDS TQQQIYESTL PKLFSNFKSC CKKQFIDIED
     KEQFQIAYGQ QQILEQQEDS FQIPSLKVVS IRSSKLINIQ QHEDDIKKFE NQFLLIELQQ
     TKFDFDQFIQ DVIKNKNFAH CGFPIQQQCE VMAILRPDHL HLLDGVKLQS IQMLKDYSKK
     DHNKIYKEIR NKTLNQYEKC MKLDCSTFLI VKQYKHYLRD NNNQLSYPQE QYRELVYPFE
     FVFPDQKVKF NVPNFEDFQI DRSVVIFHEK KNGATGIIKQ IDKKLTVQIT AYPTLLGYDY
     IHSDIYYSLQ IVSEKLQCSV KTLLNLLGSV VVNMEDKESK IADQLDIGLN IINRTNNQLV
     PELVRLPQAD QYATGSSNSL KNASLITMQI QKSMLKSLNQ RNCPINAKDL FPNSTDPNID
     LLKIYIWILQ LPESQYLLQG SSSKVAQIKI HKKPILNNNI NTTKKVDPGF AVQQTTQTFL
     PPFFIKHPTI HKIGDRVVNL NYPFGIYGTV VGLLEQKEIM VQVLWDQKHI GFTNLGGRYD
     LLSCSTCKFT EIFNLSNEDW RMNLAKRGCH QGEYWDLWTK VYKPDFKSRA IEFNDQLKEQ
     NPFKQLVELP VEVKPKVMVK EKEAPQGFEL IQKLAQEQPN LITNQPLQGI KEELIEQNED
     EAQKEIKKLF QLYQQKDLQS QGEQQKQSQK QNDEDGSKVQ PQQVEENDDK QQPQSQIKQQ
     VQPQQIKKVL TKKKDQQLQQ
//