ID A0FK57_SOLLC Unreviewed; 322 AA.
AC A0FK57;
DT 28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Gibberellin 2-oxidase 2 {ECO:0000313|EMBL:ABK15560.1, ECO:0000313|EnsemblPlants:Solyc07g056670.3.1};
GN Name=GA2ox2 {ECO:0000313|EMBL:ABK15560.1};
GN Synonyms=100037505 {ECO:0000313|EnsemblPlants:Solyc07g056670.3.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EMBL:ABK15560.1};
RN [1] {ECO:0000313|EMBL:ABK15560.1}
RP NUCLEOTIDE SEQUENCE.
RA Xiao J., Zhang J., Ye Z.;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABK15560.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17676476; DOI=10.1080/10425170701462183;
RA Xiao J.H., Zhang J.H., Zhang Y.Y., Wang T.T., Chen R.G., Li H.X., Ye Z.B.;
RT "Isolation and expression of GA 2-oxidase2 in tomato.";
RL DNA Seq. 18:472-477(2007).
RN [3] {ECO:0000313|EnsemblPlants:Solyc07g056670.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc07g056670.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [4] {ECO:0000313|EnsemblPlants:Solyc07g056670.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc07g056670.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00008056, ECO:0000256|RuleBase:RU003682}.
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DR EMBL; EF017805; ABK15560.1; -; mRNA.
DR RefSeq; NP_001234338.1; NM_001247409.1.
DR AlphaFoldDB; A0FK57; -.
DR STRING; 4081.A0FK57; -.
DR PaxDb; 4081-Solyc07g056670-2-1; -.
DR EnsemblPlants; Solyc07g056670.3.1; Solyc07g056670.3.1; Solyc07g056670.3.
DR GeneID; 100037505; -.
DR Gramene; Solyc07g056670.3.1; Solyc07g056670.3.1; Solyc07g056670.3.
DR KEGG; sly:100037505; -.
DR eggNOG; KOG0143; Eukaryota.
DR HOGENOM; CLU_010119_16_3_1; -.
DR InParanoid; A0FK57; -.
DR OMA; IHENIDG; -.
DR OrthoDB; 1057251at2759; -.
DR BRENDA; 1.14.11.13; 3101.
DR Proteomes; UP000004994; Chromosome 7.
DR ExpressionAtlas; A0FK57; baseline and differential.
DR GO; GO:0052634; F:C-19 gibberellin 2-beta-dioxygenase activity; IBA:GO_Central.
DR GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009805; P:coumarin biosynthetic process; IEA:UniProt.
DR GO; GO:0045487; P:gibberellin catabolic process; IBA:GO_Central.
DR GO; GO:0009416; P:response to light stimulus; IBA:GO_Central.
DR GO; GO:0002238; P:response to molecule of fungal origin; IEA:UniProt.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR47990; 2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR47990:SF226; GIBBERELLIN 2-OXIDASE 2; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR PRINTS; PR00682; IPNSYNTHASE.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 2: Evidence at transcript level;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU003682};
KW Metal-binding {ECO:0000256|RuleBase:RU003682};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW Vitamin C {ECO:0000256|ARBA:ARBA00022896}.
FT DOMAIN 162..270
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 322 AA; 36044 MW; 0B8A23C6894FE4FC CRC64;
MVILSKQTSF FNGVPLIDLS KPDSKNLIVN ACEEFGFFKI INHDVPMEFI SKLESEAIKF
FSSPLSEKLK AGPADPFGYG NKQIGTNGDC GRVEHILVST NSEFNYQKFA SILGVNPENI
RAAVNDYVSA VKKMSCDILE MLAEGLKIYP TNVFSKLLMD ENSDSVFRLN HYPPCSEIER
LNDNNNDLIG FGEHTDPQII SILRSNNTSG LQILLKDGHW ISVPPDENSF FVNVGDSLQV
MTNGRFKSVK HRVLANSVKS RLSMIYFGGP PLSEKIAPLA SLMEGEDSSL YKEFTWFEYK
KSAYKTRLAD NRLILFEKIA AS
//
