ID A0JRI8_ARTS2 Unreviewed; 313 AA.
AC A0JRI8;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=peptide chain release factor N(5)-glutamine methyltransferase {ECO:0000256|ARBA:ARBA00012771};
DE EC=2.1.1.297 {ECO:0000256|ARBA:ARBA00012771};
GN OrderedLocusNames=Arth_0257 {ECO:0000313|EMBL:ABK01658.1};
OS Arthrobacter sp. (strain FB24).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=290399 {ECO:0000313|EMBL:ABK01658.1, ECO:0000313|Proteomes:UP000000754};
RN [1] {ECO:0000313|Proteomes:UP000000754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FB24 {ECO:0000313|Proteomes:UP000000754};
RX PubMed=24501649; DOI=10.4056/sigs.4438185;
RA Nakatsu C.H., Barabote R., Thompson S., Bruce D., Detter C., Brettin T.,
RA Han C., Beasley F., Chen W., Konopka A., Xie G.;
RT "Complete genome sequence of Arthrobacter sp. strain FB24.";
RL Stand. Genomic Sci. 9:106-116(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-
CC methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release
CC factor] + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42896, Rhea:RHEA-
CC COMP:10271, Rhea:RHEA-COMP:10272, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:30011, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:61891; EC=2.1.1.297;
CC Evidence={ECO:0000256|ARBA:ARBA00000932};
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DR EMBL; CP000454; ABK01658.1; -; Genomic_DNA.
DR AlphaFoldDB; A0JRI8; -.
DR STRING; 290399.Arth_0257; -.
DR KEGG; art:Arth_0257; -.
DR eggNOG; COG2890; Bacteria.
DR HOGENOM; CLU_018398_4_2_11; -.
DR Proteomes; UP000000754; Chromosome.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004556; HemK-like.
DR InterPro; IPR022446; MeTrfrase_put.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR NCBIfam; TIGR00536; hemK_fam; 1.
DR NCBIfam; TIGR03704; PrmC_rel_meth; 1.
DR PANTHER; PTHR18895; HEMK METHYLTRANSFERASE; 1.
DR PANTHER; PTHR18895:SF74; MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE; 1.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:ABK01658.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000754};
KW Transferase {ECO:0000313|EMBL:ABK01658.1}.
FT DOMAIN 135..222
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
FT REGION 25..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 33109 MW; 73A3A501DE624881 CRC64;
MHRLFPANPK VAWYLSGFGS MKPTDPELRE LPLPPERPMP PSRTVPSDSP EGRRPDESVQ
RLRAAGCVFA EEEALLLTGA AASAAELESM IERRVAGLPL EHILGWAEFC GLRIGVTAGV
FVPRRRTGFL VRQAELLLRA THDGGVPRVV DLCCGSGAVG AALAARVAGI ELHAADLDPT
AVLCAKGNIE PAGGHVHQGD LFEALPARLR GRITVLVANA PYVPTAAIGT MPPEARAHEP
LMSLDGGPDG LDIQRRVIAG APAWLAPGGH VLIETSRRQA RRTIGLMRGA GLAARLASDP
ELDATVAIGL RRD
//
