ID A0KHE4_AERHH Unreviewed; 451 AA.
AC A0KHE4;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=AMP nucleosidase {ECO:0000256|ARBA:ARBA00011985};
DE EC=3.2.2.4 {ECO:0000256|ARBA:ARBA00011985};
DE AltName: Full=AMP nucleosidase {ECO:0000256|ARBA:ARBA00031983};
GN OrderedLocusNames=AHA_1154 {ECO:0000313|EMBL:ABK39308.1};
OS Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK39308.1, ECO:0000313|Proteomes:UP000000756};
RN [1] {ECO:0000313|EMBL:ABK39308.1, ECO:0000313|Proteomes:UP000000756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 /
RC KCTC 2358 / NCIMB 9240 / NCTC 8049
RC {ECO:0000313|Proteomes:UP000000756};
RX PubMed=16980456; DOI=10.1128/JB.00621-06;
RA Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.,
RA Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL J. Bacteriol. 188:8272-8282(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=AMP + H2O = adenine + D-ribose 5-phosphate;
CC Xref=Rhea:RHEA:20129, ChEBI:CHEBI:15377, ChEBI:CHEBI:16708,
CC ChEBI:CHEBI:78346, ChEBI:CHEBI:456215; EC=3.2.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000274};
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DR EMBL; CP000462; ABK39308.1; -; Genomic_DNA.
DR RefSeq; WP_011705076.1; NC_008570.1.
DR RefSeq; YP_855695.1; NC_008570.1.
DR AlphaFoldDB; A0KHE4; -.
DR STRING; 380703.AHA_1154; -.
DR EnsemblBacteria; ABK39308; ABK39308; AHA_1154.
DR GeneID; 77275243; -.
DR KEGG; aha:AHA_1154; -.
DR PATRIC; fig|380703.7.peg.1159; -.
DR eggNOG; COG1611; Bacteria.
DR HOGENOM; CLU_047550_0_0_6; -.
DR OrthoDB; 9801098at2; -.
DR Proteomes; UP000000756; Chromosome.
DR GO; GO:0008714; F:AMP nucleosidase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.450; -; 1.
DR Gene3D; 3.30.1850.10; MoCo carrier protein-like; 1.
DR InterPro; IPR031100; LOG_fam.
DR InterPro; IPR049788; PpnN.
DR InterPro; IPR037153; PpnN-like_sf.
DR InterPro; IPR021826; PpnN_C.
DR InterPro; IPR027820; PpnN_N.
DR NCBIfam; NF038390; Nsidase_PpnN; 1.
DR PANTHER; PTHR43393; CYTOKININ RIBOSIDE 5'-MONOPHOSPHATE PHOSPHORIBOHYDROLASE; 1.
DR PANTHER; PTHR43393:SF1; PYRIMIDINE_PURINE NUCLEOTIDE 5'-MONOPHOSPHATE NUCLEOSIDASE; 1.
DR Pfam; PF14793; DUF4478; 1.
DR Pfam; PF03641; Lysine_decarbox; 1.
DR Pfam; PF11892; PpnN_C; 1.
DR SUPFAM; SSF102405; MCP/YpsA-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000756}.
FT DOMAIN 4..110
FT /note="Pyrimidine/purine nucleotide 5'-monophosphate
FT nucleosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14793"
FT DOMAIN 330..450
FT /note="Pyrimidine/purine nucleotide 5'-monophosphate
FT nucleosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11892"
SQ SEQUENCE 451 AA; 50204 MW; 8065DBD97AC5E28E CRC64;
MITHINPVGS MDLLSQLEVD RLKQTASSDI YQLFRNCSLA VLNSGSHTDS SKEILERFKS
FDIHVIRRER GVKLELFNAP EHAFVDGEII RGIQEHLFSV LRDILYVSTQ LESNRLVNLT
SSTHISNVVF AILRNAKAIL PGADPNLVVC WGGHSINEIE YQYTRAVGSE LGLRELNICT
GCGPGAMEGP MKGAAVGHAK QRVRNGRYIG LTEPSIIAAE PPNPIVNELV ILPDIEKRLE
AFVRLGHGII IFPGGVGTAE ELLYLLGIMM HPANERQPMP IILTGPKESA DYFRAIDDFV
KATLGEPATS LYRIIVGDAP EVARVMKEAM PKIREYRKSV GDAYSFNWSL KIEPEFQLPF
EPDHANMASL DLHRNQPPQL LAANLRRAFS GIVAGNVKEG GIRAIEKKGP FKLHGDKELM
HLMDKLLESF VKQQRMKLPG SQYVPCYEIV R
//
