ID A0KL21_AERHH Unreviewed; 555 AA.
AC A0KL21;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ABK38415.1};
GN OrderedLocusNames=AHA_2458 {ECO:0000313|EMBL:ABK38415.1};
OS Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK38415.1, ECO:0000313|Proteomes:UP000000756};
RN [1] {ECO:0000313|EMBL:ABK38415.1, ECO:0000313|Proteomes:UP000000756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 /
RC KCTC 2358 / NCIMB 9240 / NCTC 8049
RC {ECO:0000313|Proteomes:UP000000756};
RX PubMed=16980456; DOI=10.1128/JB.00621-06;
RA Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.,
RA Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL J. Bacteriol. 188:8272-8282(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CP000462; ABK38415.1; -; Genomic_DNA.
DR RefSeq; WP_011706289.1; NC_008570.1.
DR RefSeq; YP_856972.1; NC_008570.1.
DR AlphaFoldDB; A0KL21; -.
DR STRING; 380703.AHA_2458; -.
DR EnsemblBacteria; ABK38415; ABK38415; AHA_2458.
DR KEGG; aha:AHA_2458; -.
DR PATRIC; fig|380703.7.peg.2456; -.
DR eggNOG; COG0840; Bacteria.
DR eggNOG; COG4564; Bacteria.
DR HOGENOM; CLU_000445_107_21_6; -.
DR OrthoDB; 2489132at2; -.
DR Proteomes; UP000000756; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR033480; sCache_2.
DR PANTHER; PTHR32089:SF55; METHYL ACCEPTING SENSORY TRANSDUCER WITH CACHE_2 SMALL MOLECULE BINDING DOMAIN; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF17200; sCache_2; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 224..278
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 283..519
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 555 AA; 60472 MW; A29DD0804D315978 CRC64;
MTLKQKILLL GAVPVLLMAL VVNLSNYMIS KSDLEADLVV ARENAIKDRK ALLSSYLMLA
KTAIDAVYNQ PDSPAVRKQV TELLRPLRYS SDGYFFVYDF QGNTILLPTR PEMEGKNRWQ
DKDAKGKLLI QEIVKAARQG DGFSEYWTAK PSIGRDAPKL SFNLVLDKYQ WVIGTGFYID
DIDNELAVLR TERESNMRDS LQSSVLLILV ILGVTLAATV VIGNRVTRPL ADAVSALNDI
ADGEGDLTQR LKVQSHDEIG QLATAFNRFV TRIQSVVSQV GETSNHLFSA VEKLHHLSEH
YDHQMHGHSR ETDQVVTAVT EMSSTAQEVA ASASNAATAT SDAARESDAA RGVVGTAINS
INRLVGEVHT ASGVIEQLAQ ETAKIGSVVE VIRGIAEQTN LLALNAAIEA ARAGEQGRGF
AVVADEVRSL AGRTQQSTKE INEMLQRLQG GVKQAVDVMQ ASEERSQETV QEASHIATSL
DSMVMAVSTI NDMNIQIATA AEEQHAVSEE INKNLVAIQQ IVSELTDAAV ESNSTTRDLA
STGDKLRKLV SQFRY
//
