ID   A0KMQ2_AERHH            Unreviewed;       512 AA.
AC   A0KMQ2;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Bacterial leucyl aminopeptidase {ECO:0000313|EMBL:ABK38191.1};
DE            EC=3.4.11.10 {ECO:0000313|EMBL:ABK38191.1};
GN   OrderedLocusNames=AHA_3051 {ECO:0000313|EMBL:ABK38191.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS   13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK38191.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK38191.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 /
RC   KCTC 2358 / NCIMB 9240 / NCTC 8049
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.,
RA   Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA   Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
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DR   EMBL; CP000462; ABK38191.1; -; Genomic_DNA.
DR   RefSeq; YP_857553.1; NC_008570.1.
DR   AlphaFoldDB; A0KMQ2; -.
DR   STRING; 380703.AHA_3051; -.
DR   MEROPS; M28.004; -.
DR   EnsemblBacteria; ABK38191; ABK38191; AHA_3051.
DR   KEGG; aha:AHA_3051; -.
DR   PATRIC; fig|380703.7.peg.3051; -.
DR   eggNOG; COG2234; Bacteria.
DR   HOGENOM; CLU_025866_2_1_6; -.
DR   OrthoDB; 9789219at2; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd03879; M28_AAP; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR045175; M28_fam.
DR   InterPro; IPR007484; Peptidase_M28.
DR   PANTHER; PTHR12147:SF26; ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1; 1.
DR   PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|EMBL:ABK38191.1};
KW   Hydrolase {ECO:0000313|EMBL:ABK38191.1};
KW   Protease {ECO:0000313|EMBL:ABK38191.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756}.
FT   DOMAIN          300..500
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
FT   REGION          53..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..67
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   512 AA;  54791 MW;  80047A421E38304F CRC64;
     MPLFTPALLG ARAPPHPCPP ASRADMAQFD SLCQPPRSGP HAASAAGALR SFPSPAQSSS
     GYPQRGAVDS RSCSGPHRTG VGSRQMGKFA VFSLWLDWAS RLMTPTWHTC LQLILEGSAM
     KPLLTALLLP LLPLAVQAAE PVWITVGADS GVELKQVKAK LAPLFSASGA PVQLAQVEAS
     ELGTLSHLMH EGHQRCGGYV VHSTLADALQ SMAQPISQNL FSAPPLTQGA SVNRLLPYLD
     QGNIVGTISQ LASWRNRYYT TTTGVQSADW VAGQWQTLSA PLPWASVSRV KHSGYPQQSV
     VLTLKGSRYP DEVVVLGGHL DSTAGSAPNS RTLAPGADDD ASGIATLTEV LRVIAEQGRQ
     PERTLQFIGY AAEEVGLRGS KDIATRYKAA NTKVLAALQL DMTNYQGSAE DIVFMTDYTD
     KGLTGYLAQL LDAYLPQIRY GYDSCGYGCS DHASWHNQGY PAAMPFESRF NDYNPNIHTA
     QDTLQNSDPS AAHALKFAQL ATSFAIEMGK IN
//