ID A0KN72_AERHH Unreviewed; 517 AA.
AC A0KN72;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN OrderedLocusNames=AHA_3232 {ECO:0000313|EMBL:ABK35973.1};
OS Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK35973.1, ECO:0000313|Proteomes:UP000000756};
RN [1] {ECO:0000313|EMBL:ABK35973.1, ECO:0000313|Proteomes:UP000000756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 /
RC KCTC 2358 / NCIMB 9240 / NCTC 8049
RC {ECO:0000313|Proteomes:UP000000756};
RX PubMed=16980456; DOI=10.1128/JB.00621-06;
RA Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.,
RA Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL J. Bacteriol. 188:8272-8282(2006).
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DR EMBL; CP000462; ABK35973.1; -; Genomic_DNA.
DR RefSeq; WP_011707007.1; NC_008570.1.
DR RefSeq; YP_857723.1; NC_008570.1.
DR AlphaFoldDB; A0KN72; -.
DR STRING; 380703.AHA_3232; -.
DR EnsemblBacteria; ABK35973; ABK35973; AHA_3232.
DR KEGG; aha:AHA_3232; -.
DR PATRIC; fig|380703.7.peg.3227; -.
DR eggNOG; COG2199; Bacteria.
DR HOGENOM; CLU_041123_0_0_6; -.
DR OrthoDB; 5582079at2; -.
DR Proteomes; UP000000756; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 272..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 375..501
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT REGION 498..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 58209 MW; 8792BDE00E6BC1C0 CRC64;
MIQWLISRRY YLLTSLTLLL GTLVLVVTLA LATASYLRSI DKTVAGYGHM LSSLDAALIH
ELVLANQRQL AVLEASLDKA AIARGEPADN PLWAIAHQIK RDSHYIYFYH PQTDRISSYP
AWQQPVEYRA ASRPWYRALS MPGDELIWLG PYQEYGSDKQ ILTLIKRVKG LDGQLLGLLM
VDMSFNAIQQ ALQRAMGRNQ AAIYISSRGG EQLVVGCNMA LYQPPVTTAG VVGSGLEVIW
HGRHLRRELE GIDWDLNIYL PPELFHDGLE EALLMVVLPL LSLFAIWFCS INFLVRVFNQ
EQALVAGSLT GIVRDPTQTP CQLKTWFVHS SLSEIDQVRA SFLQGQDALL HDPLTGIMNR
RAFTQRRSEL EESATPHWLL LFDVDNFKRI NDNWGHTVGD GVLCRVAELL VAELGSGCVY
RIGGDEFAAL LPWPRSELES GLSRLLARVR NQQWREFREA VTLSVGGAHS PDDGVLLFER
VDECLYRSKR LGRDGWSLTE QTRQEQGADR SCHMDNG
//
