ID A0KQL2_AERHH Unreviewed; 443 AA.
AC A0KQL2;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Glutamine synthetase {ECO:0000313|EMBL:ABK39035.1};
GN OrderedLocusNames=AHA_4140 {ECO:0000313|EMBL:ABK39035.1};
OS Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK39035.1, ECO:0000313|Proteomes:UP000000756};
RN [1] {ECO:0000313|EMBL:ABK39035.1, ECO:0000313|Proteomes:UP000000756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 /
RC KCTC 2358 / NCIMB 9240 / NCTC 8049
RC {ECO:0000313|Proteomes:UP000000756};
RX PubMed=16980456; DOI=10.1128/JB.00621-06;
RA Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.,
RA Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL J. Bacteriol. 188:8272-8282(2006).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
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DR EMBL; CP000462; ABK39035.1; -; Genomic_DNA.
DR RefSeq; WP_011707799.1; NC_008570.1.
DR RefSeq; YP_858563.1; NC_008570.1.
DR AlphaFoldDB; A0KQL2; -.
DR STRING; 380703.AHA_4140; -.
DR EnsemblBacteria; ABK39035; ABK39035; AHA_4140.
DR GeneID; 77271842; -.
DR KEGG; aha:AHA_4140; -.
DR PATRIC; fig|380703.7.peg.4100; -.
DR eggNOG; COG0174; Bacteria.
DR HOGENOM; CLU_017290_0_0_6; -.
DR OrthoDB; 9789509at2; -.
DR Proteomes; UP000000756; Chromosome.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.10.20.70; Glutamine synthetase, N-terminal domain; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR036651; Gln_synt_N_sf.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR PANTHER; PTHR43785; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE; 1.
DR PANTHER; PTHR43785:SF3; GLN-SYNT_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF54368; Glutamine synthetase, N-terminal domain; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000000756}.
FT DOMAIN 14..103
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 110..443
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 443 AA; 50414 MW; A21CEE0245DD48E1 CRC64;
MDSIKGWMES NRITEVECLF PDFTGNARGK IIPANKFLRE GGMRLPEVIF TQTVTGEYPD
DDSMIDPLER DMQLYPDPNT IRFVPWALEP TAQVIHDCFD INGKLIDIAP RSVLRRVLSF
YEKQGWKPVV APELEFYLVK RNEDPDYPLV PPVGRNGRPE TARQSFSIDA VNEFDPIFED
MYDYCEAQEL EVDTLIHESG AAQMEINFLH GDAVDLADQV FLFKRTMREA AHRHGIYATF
MAKPMSDEPG SAMHIHQSLE DVNGRNLFGT ENGGHSELFM HFIAGLQKYT PAVTALLAPN
VNSYRRLTFG ESAPRNVQWG VENRTCGLRV PFSEASARRV ENRFAGADAN PYLALAATLA
CGYLGMMEKL EPLPEMKSSA YELPYSLPRS LEEALSHLEQ CDPIKEMLGE RFTRAFVAVK
RKEYETYFGV ISRWEREFLL LNV
//
