ID A0L9S8_MAGMM Unreviewed; 971 AA.
AC A0L9S8;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) {ECO:0000313|EMBL:ABK44721.1};
GN OrderedLocusNames=Mmc1_2220 {ECO:0000313|EMBL:ABK44721.1};
OS Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Magnetococcales;
OC Magnetococcaceae; Magnetococcus.
OX NCBI_TaxID=156889 {ECO:0000313|EMBL:ABK44721.1, ECO:0000313|Proteomes:UP000002586};
RN [1] {ECO:0000313|Proteomes:UP000002586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC {ECO:0000313|Proteomes:UP000002586};
RX PubMed=19465526; DOI=10.1128/AEM.02874-08;
RA Schubbe S., Williams T.J., Xie G., Kiss H.E., Brettin T.S., Martinez D.,
RA Ross C.A., Schuler D., Cox B.L., Nealson K.H., Bazylinski D.A.;
RT "Complete genome sequence of the chemolithoautotrophic marine magnetotactic
RT coccus strain MC-1.";
RL Appl. Environ. Microbiol. 75:4835-4852(2009).
RN [2] {ECO:0000313|EMBL:ABK44721.1, ECO:0000313|Proteomes:UP000002586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC {ECO:0000313|Proteomes:UP000002586};
RX PubMed=22581902;
RA Bazylinski D.A., Williams T.J., Lefevre C.T., Berg R.J., Zhang C.L.,
RA Bowser S.S., Dean A.J., Beveridge T.J.;
RT "Magnetococcus marinus gen. nov., sp. nov., a marine, magnetotactic
RT bacterium that represents a novel lineage (Magnetococcaceae fam. nov.;
RT Magnetococcales ord. nov.) at the base of the Alphaproteobacteria.";
RL Int. J. Syst. Evol. Microbiol. 0:0-0(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000471; ABK44721.1; -; Genomic_DNA.
DR RefSeq; WP_011713842.1; NC_008576.1.
DR AlphaFoldDB; A0L9S8; -.
DR STRING; 156889.Mmc1_2220; -.
DR KEGG; mgm:Mmc1_2220; -.
DR eggNOG; COG4564; Bacteria.
DR eggNOG; COG5000; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_20_5; -.
DR OrthoDB; 7251575at2; -.
DR Proteomes; UP000002586; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR033480; sCache_2.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF13426; PAS_9; 2.
DR Pfam; PF17200; sCache_2; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002586};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 220..272
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 359..411
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 408..453
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 481..533
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 565..698
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 707..961
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 971 AA; 110110 MW; E0DDF5B50647EEE8 CRC64;
MDFQYGDKIL FKHITIHNRM LVMVGCAIIS LMFVGGFGLR ELHSNLMQDR KNKTQHLVQV
VVSTLAAYQA QVVAGTLSLR DAQQQAADMV AHMRYGQENY FWINDLNIKM VVHPLRPELN
GQDLSTIKDA NGVFLFTRFV DVVQRQGSGF VEYLWPKPGS IEAVPKISYV EKFAPWGWMV
GSGIYVDDVE HIFQDAASAF MAVILTALLV VWAISVKIGR SITRPLFQTR QAMLRLANGD
LDVPLEDMDR SELGDLSQAL RVFRDQFAIN EGLRLEREES LKQAAEKREE LARIIEISHT
VVLSWENDEE WSLSYVSENC YRILQSGLKS LVLKPLVNPE DLPQMEALLA AGGDASRWVK
LEFRLCLGSE EPRWFECCVL PIKDDHAEVV QYHGVLHDIT ERRKGEHDLR LAQVLFRTTN
EALMISSRDN KIEMVNPAFS RITGYQLDEV LGKGPDLLQS GRHDAPFYTQ MWHALQQDGA
WEGEIWNRRK SGETYPEWLS IATVTNDKGE TVQYVAAFSD ITKRKQAEET ILHQANYDFL
TDLPNRNLFH DRLQTELKRS QRSGQQVALL FIDLDRFKFV NDTLGHNVGD QLLREVAIRL
GHCVRESDTI ARLGGDEFTV ILPELHGPEG VARLAQGMID KLEERYCIQD HELFISASIG
ITIYPEDADN MMDLVKNADV AMYRAKENGR GSFCFYTAEM NADARQLHKI EQALRVALEE
GQFWIHYQPY VQQSSGLITG VEALIRWRNS AGEIVYPDQF IPVAEETGLI VPIGLWVLRS
VIGVIAQWQR EGHPDITFSV NVSARQFQEG HLVGQIKAAL QENQINPQSL MLEITESLMI
RDPEHTLNML KEIKALGVRV ALDDFGTGYS SLGYLKQFPI DLLKIDRSFI NGIANSQDDE
TMVSAIVSMA HSLGVGVIGE GIENDQQLQR VNLHACDYVQ GFFYSRPMPY DELALFFEGY
QKSHLGLAES E
//
