ID A0LAQ0_MAGMM Unreviewed; 712 AA.
AC A0LAQ0;
DT 12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABK45043.1};
GN OrderedLocusNames=Mmc1_2543 {ECO:0000313|EMBL:ABK45043.1};
OS Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Magnetococcales;
OC Magnetococcaceae; Magnetococcus.
OX NCBI_TaxID=156889 {ECO:0000313|EMBL:ABK45043.1, ECO:0000313|Proteomes:UP000002586};
RN [1] {ECO:0000313|Proteomes:UP000002586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC {ECO:0000313|Proteomes:UP000002586};
RX PubMed=19465526; DOI=10.1128/AEM.02874-08;
RA Schubbe S., Williams T.J., Xie G., Kiss H.E., Brettin T.S., Martinez D.,
RA Ross C.A., Schuler D., Cox B.L., Nealson K.H., Bazylinski D.A.;
RT "Complete genome sequence of the chemolithoautotrophic marine magnetotactic
RT coccus strain MC-1.";
RL Appl. Environ. Microbiol. 75:4835-4852(2009).
RN [2] {ECO:0000313|EMBL:ABK45043.1, ECO:0000313|Proteomes:UP000002586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1437 / JCM 17883 / MC-1
RC {ECO:0000313|Proteomes:UP000002586};
RX PubMed=22581902;
RA Bazylinski D.A., Williams T.J., Lefevre C.T., Berg R.J., Zhang C.L.,
RA Bowser S.S., Dean A.J., Beveridge T.J.;
RT "Magnetococcus marinus gen. nov., sp. nov., a marine, magnetotactic
RT bacterium that represents a novel lineage (Magnetococcaceae fam. nov.;
RT Magnetococcales ord. nov.) at the base of the Alphaproteobacteria.";
RL Int. J. Syst. Evol. Microbiol. 0:0-0(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC {ECO:0000256|ARBA:ARBA00005381}.
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DR EMBL; CP000471; ABK45043.1; -; Genomic_DNA.
DR RefSeq; WP_011714162.1; NC_008576.1.
DR AlphaFoldDB; A0LAQ0; -.
DR STRING; 156889.Mmc1_2543; -.
DR KEGG; mgm:Mmc1_2543; -.
DR eggNOG; COG2114; Bacteria.
DR HOGENOM; CLU_021956_0_0_5; -.
DR OrthoDB; 9762462at2; -.
DR Proteomes; UP000002586; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002586};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 371..424
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 451..583
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 712 AA; 79714 MW; 5202A9F32C2EE8D8 CRC64;
MMHNRQVELR IGISLAFGLV MALLTVSLVG YLYWDNSKLI LETASKTMAR ATLQVDRDVQ
GLLAPVERVV QATAELARVD TGSLQTVQGL GYLQRQLVSL PQVFSFYLGF ENSGDFYQVF
AVPPTLKQLG PSKEDLPQGV RYAARLLNES SGHRADSFIF YKEWGDVVKV DRGPVRYDPR
VRPWYKKAWE VPQVAISDAY VFASSKLIGL TLSSHVSTPS DIKIGVVGAD ITLDTLSSFL
YKAQIGLSGR VFLLNADNYL VGHREPDMGV EVTEEKVRLR KATEVRDPLV AEAVQHWQKS
GVDRFETTLG PNGDEYMVSF AKIGGSLGWT AGVLVQKEEL IGPLADASIK ILVAGSLAIS
LAIFLFMMLS QLLTRPLSKV TQETVKIRRF NLEGNLNLTS YISEVRQLVD AVETMKRSLR
SFSVYVPKEI VRAIVEDEDE TSIGSRRQPL TVMFSDIKGF SNISEELPPE QLVGSLSEYM
EQMSQPIHRY KGTIDKFIGD AIMALWNAPS KDPDHVVNAC RAMLGCHRAG LALAETFAKN
GRTPFYTRFG LHTGEAVVGN VGSTERMQYS AFGNMVNMAS RLESMNKQYD TELMVSEHVA
RVAQPHFYLR RLDKVVPVGN THPMYVYELM GEKDPKSPLA ATEEQKLKLS LWHAVMDHYE
ARDWHAVLEK LALYKQSFPH DKGAEQIEKR CHLFIVTPPP ADWDGAEWLK NK
//
