ID   A0LER8_SYNFM            Unreviewed;       964 AA.
AC   A0LER8;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Type I phosphodiesterase/nucleotide pyrophosphatase {ECO:0000313|EMBL:ABK15920.1};
GN   OrderedLocusNames=Sfum_0219 {ECO:0000313|EMBL:ABK15920.1};
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Thermodesulfobacteriota; Syntrophobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543 {ECO:0000313|EMBL:ABK15920.1, ECO:0000313|Proteomes:UP000001784};
RN   [1] {ECO:0000313|EMBL:ABK15920.1, ECO:0000313|Proteomes:UP000001784}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB {ECO:0000313|Proteomes:UP000001784};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J., Sieber J.,
RA   Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000478; ABK15920.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0LER8; -.
DR   STRING; 335543.Sfum_0219; -.
DR   KEGG; sfu:Sfum_0219; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG3118; Bacteria.
DR   eggNOG; COG3379; Bacteria.
DR   HOGENOM; CLU_340615_0_0_7; -.
DR   InParanoid; A0LER8; -.
DR   Proteomes; UP000001784; Chromosome.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR002591; Phosphodiest/P_Trfase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR   PANTHER; PTHR10151:SF126; PHOSPHODIESTERASE; 1.
DR   Pfam; PF01663; Phosphodiest; 1.
DR   Pfam; PF13432; TPR_16; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001784};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   REPEAT          588..621
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          656..689
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   964 AA;  107284 MW;  F95FAB27051660A3 CRC64;
     MIYWIMRLHF HSASTRGFAV AKVPDRRVLL IGWDAADWKV IGPLLDAGKM PHLDRFINSG
     VMGNLATLYP DLSPMLWTSI ATGKRPFKHG ILGFIEPDPH TGGIRPITNL SRKTKTIWNI
     LSQTGRKCNV VGWWPSHPAE PINGVMVSNR YQKAVGPLDR PWPLVPGTVH PARLVRNLAN
     LRFHPQQLHS GHIHPFVPKF SEIDQDRDHR LESLAKIISE CLSIEAAALA LMHHEPWDFT
     AVYFDGIDHF CHGFMRYHPP RADWVDERDF ELYSRVVESG YILHDIMLGR LLEKAGEDAT
     VLLVSDHGFK SDNLRPRHIP REPAGPAVMH RHYGVFAMKG PGIKEDERVY GAGILDVCPT
     VLSLFGLPVG LDMDGKPLGG AFQDRPGIET IASWDQLEGS AGMHGPEMKI DPVDASEAIK
     QLVALGYIEK PSEDREEAVA ETVRELRYNQ ARSCMDANRY ADAVSILEDL VEGWPFEHRF
     GIQLVTCYQA MGWLADARKL LESLFRRKEE DALASREKLR LFTEERTGKK PEEWSEEELR
     ELRELRGRSS WNPYAVEYLM GSLLFSEGQK EAALDHLKRA EAAAPGEPGI HAKLGAVYLR
     MKRWEDAELS FGKAVALDPD CAEAYRGLAL CHLPRRRNTD AAQAALEAIG RVYFDPMSHF
     LLGVALHRLG HIPRALEALK VAVSQNPNFP RAHRRLSLIY KNRLQDVERA AIHHALAVEA
     ARRVWNVRRK RVATSREEAA EAIGMRAGIE PVAAKVDTCS VPAVSPTCGA VDLRETVVVV
     TGLPRSGTSM MMQMLAAGGI EPLTDGKREP DALNPKGYFE FEPAKNLQRD ASWLPGARGK
     AVKVVAQLLP HLSPGLDYRV VFMEREMEEV LQSQERMLGH RSKEGAVPAS GKLKEVFSAQ
     VSAIRKMLAS RGIPTLSIAY GDSLEKPRET AARVNAFLGG GLDEGRMAAA VDPRLKTVIG
     AKSA
//