ID   A0P7A3_9PROT            Unreviewed;       309 AA.
AC   A0P7A3;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Probable nucleoside-diphosphate-sugar epimerase protein {ECO:0000313|EMBL:EAV47413.1};
GN   ORFNames=MB2181_05030 {ECO:0000313|EMBL:EAV47413.1};
OS   Methylophilales bacterium HTCC2181.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales; OM43 clade.
OX   NCBI_TaxID=383631 {ECO:0000313|EMBL:EAV47413.1, ECO:0000313|Proteomes:UP000054262};
RN   [1] {ECO:0000313|EMBL:EAV47413.1, ECO:0000313|Proteomes:UP000054262}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2181 {ECO:0000313|EMBL:EAV47413.1,
RC   ECO:0000313|Proteomes:UP000054262};
RA   Giovannoni S., Vergin K., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA   Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000256|ARBA:ARBA00007637}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAV47413.1}.
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DR   EMBL; AAUX01000001; EAV47413.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0P7A3; -.
DR   OrthoDB; 9802815at2; -.
DR   Proteomes; UP000054262; Unassembled WGS sequence.
DR   CDD; cd08946; SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43000:SF7; DTDP-D-GLUCOSE 4,6-DEHYDRATASE; 1.
DR   PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054262}.
FT   DOMAIN          6..226
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   309 AA;  33883 MW;  4FD8EEE83E1E5329 CRC64;
     MKIQSVLVTG AHGFIGRNVA RHLSRQGLKV IGIGHGKWSS VDEQKLWGIS EWRSSDITVD
     GLRACEVVPD SIIHCAGSGS VGLSIQNPLD DFERNLNTTL NVLEYVRLYA STAKVITISS
     AGVYGEVEKL PMAEGDSINP ISPYGVHKKI AEELCKSYVD HFGLNVTVLR LFSVYGPGLK
     KQLLWDACNK IMGGEYKFFG TGNELRDWIH VTDVAKLVAC LLTTSSSNFN LYNGATGLGT
     PITDILKLLF TALDSKESAI FTGSARQGDP IGYVADVTKT SQVLAWDPKI KWHQGVLEYA
     EWFKHHAIN
//