ID A0PJP7_XENTR Unreviewed; 239 AA.
AC A0PJP7;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Proline-rich transmembrane protein 1 {ECO:0000313|Ensembl:ENSXETP00000011229, ECO:0000313|RefSeq:NP_001090824.1};
DE SubName: Full=Prrt1 protein {ECO:0000313|EMBL:AAI27557.1};
GN Name=prrt1 {ECO:0000313|EMBL:AAI27557.1,
GN ECO:0000313|Ensembl:ENSXETP00000011229,
GN ECO:0000313|RefSeq:NP_001090824.1,
GN ECO:0000313|Xenbase:XB-GENE-484400};
GN Synonyms=ng5 {ECO:0000313|RefSeq:NP_001090824.1}, syndig4
GN {ECO:0000313|RefSeq:NP_001090824.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI27557.1};
RN [1] {ECO:0000313|RefSeq:NP_001090824.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAI27557.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain {ECO:0000313|EMBL:AAI27557.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000011229}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000011229};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000011229}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001090824.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CD225/Dispanin family.
CC {ECO:0000256|ARBA:ARBA00006843}.
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DR EMBL; BC127556; AAI27557.1; -; mRNA.
DR RefSeq; NP_001090824.1; NM_001097355.1.
DR PaxDb; 8364-ENSXETP00000011229; -.
DR DNASU; 100038083; -.
DR Ensembl; ENSXETT00000011229; ENSXETP00000011229; ENSXETG00000005163.
DR GeneID; 100038083; -.
DR KEGG; xtr:100038083; -.
DR AGR; Xenbase:XB-GENE-484400; -.
DR CTD; 80863; -.
DR Xenbase; XB-GENE-484400; prrt1.
DR eggNOG; ENOG502QWCK; Eukaryota.
DR HOGENOM; CLU_096299_0_0_1; -.
DR OMA; HHDNDWG; -.
DR OrthoDB; 2919628at2759; -.
DR TreeFam; TF331357; -.
DR Proteomes; UP000008143; Chromosome 8.
DR Bgee; ENSXETG00000005163; Expressed in brain and 4 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR007593; CD225/Dispanin_fam.
DR PANTHER; PTHR14948; NG5; 1.
DR PANTHER; PTHR14948:SF21; PROLINE-RICH TRANSMEMBRANE PROTEIN 1; 1.
DR Pfam; PF04505; CD225; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|RefSeq:NP_001090824.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 156..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 239 AA; 25358 MW; EFCC2D035FE61C4C CRC64;
MSSEKTGPPD SGPHNSPPPY NQPVGEGPCN GVIPGYNDPP PQPATATLPR QDPQGYLQET
PFTAPPPAPQ GYVVQTHPPG GTIPSGGYIP QGPGYPMHLQ PCTAYVPVYP VGTFLPHFYL
LQQYPAGAVP PQPGIPPPQI PPGLALLEPR RPPHDYLPIA VLTTICCFWP TGVIAIIKAV
QVRTALARGD LMSAEIASRE ARNFSFISLA VGIAAMVLCT ILTVVIIIAA QHHDNEWGP
//
