ID A0PXF1_CLONN Unreviewed; 387 AA.
AC A0PXF1;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=HTH-type transcriptional activator tipA, putative {ECO:0000313|EMBL:ABK61220.1};
GN OrderedLocusNames=NT01CX_0956 {ECO:0000313|EMBL:ABK61220.1};
OS Clostridium novyi (strain NT).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK61220.1, ECO:0000313|Proteomes:UP000008220};
RN [1] {ECO:0000313|EMBL:ABK61220.1, ECO:0000313|Proteomes:UP000008220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NT {ECO:0000313|EMBL:ABK61220.1,
RC ECO:0000313|Proteomes:UP000008220};
RX PubMed=17115055; DOI=10.1038/nbt1256;
RA Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA Zhou S.;
RT "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT NT.";
RL Nat. Biotechnol. 24:1573-1580(2006).
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DR EMBL; CP000382; ABK61220.1; -; Genomic_DNA.
DR RefSeq; WP_011721074.1; NC_008593.1.
DR AlphaFoldDB; A0PXF1; -.
DR STRING; 386415.NT01CX_0956; -.
DR KEGG; cno:NT01CX_0956; -.
DR PATRIC; fig|386415.7.peg.80; -.
DR eggNOG; COG0789; Bacteria.
DR HOGENOM; CLU_060077_0_0_9; -.
DR Proteomes; UP000008220; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01106; HTH_TipAL-Mta; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036244; TipA-like_antibiotic-bd.
DR InterPro; IPR012925; TipAS_dom.
DR PANTHER; PTHR30204:SF90; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TIPA; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF13411; MerR_1; 1.
DR Pfam; PF07739; TipAS; 2.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF89082; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000008220};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..70
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 387 AA; 45460 MW; AAEB4C1735FBC957 CRC64;
MRTVKQVSDL TGISVRLLHY YDEIGLLKPS RVTDAGYRLY DHEDIKALQQ ILFFKELDIP
LKEVKKIMSS PYFDKVEALK NQRKLLILKR KRLNALIELI NKTLNGESTM SFKEFDMSEY
FNVLEEFKTE HEDKIIKLYG SVDKYNEYIE QMKSKEGKIA KMAIKKYGSI EKYAKAIKKN
FNSGILNLAE RYDEFKKDLL EDNNPKLKEL YKKLVCDLKK EPSSAEIQQI AGEITNTAKE
DYEIFNMKNG DDHWFYMVQI FLVYPDWIKE VDKKYGSGSS KFIGKALKNY LGDKRPKLEI
LYEKLVFDLC KDPSSREIQQ IVEEISDATK ENNEFYKIDS GENHWGYMSE LYLSDSNFIK
IIDKKYGYGA SKFMGEAFKI YAERLKE
//
