ID A0PYV5_CLONN Unreviewed; 253 AA.
AC A0PYV5;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Transcription regulator (IclR family) BH2137 {ECO:0000313|EMBL:ABK61883.1};
GN OrderedLocusNames=NT01CX_1476 {ECO:0000313|EMBL:ABK61883.1};
OS Clostridium novyi (strain NT).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK61883.1, ECO:0000313|Proteomes:UP000008220};
RN [1] {ECO:0000313|EMBL:ABK61883.1, ECO:0000313|Proteomes:UP000008220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NT {ECO:0000313|EMBL:ABK61883.1,
RC ECO:0000313|Proteomes:UP000008220};
RX PubMed=17115055; DOI=10.1038/nbt1256;
RA Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA Zhou S.;
RT "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT NT.";
RL Nat. Biotechnol. 24:1573-1580(2006).
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DR EMBL; CP000382; ABK61883.1; -; Genomic_DNA.
DR RefSeq; WP_011721565.1; NC_008593.1.
DR AlphaFoldDB; A0PYV5; -.
DR STRING; 386415.NT01CX_1476; -.
DR KEGG; cno:NT01CX_1476; -.
DR PATRIC; fig|386415.7.peg.583; -.
DR eggNOG; COG1414; Bacteria.
DR HOGENOM; CLU_062618_5_5_9; -.
DR Proteomes; UP000008220; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008220};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..67
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 68..251
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 253 AA; 29210 MW; AA94132369ABE2F4 CRC64;
MQEIVQSVDR SLSILEVLSD YENGLGITEI SEKVNLHKST VHRLLATLIY KGYVEQEDKA
NKYKLTLKLF ELGNKKIQKM DLITVARPYL KELVENTNEV VHLVVREGTE IIYVGKEESQ
NTIRTHSRIG NRRPLYCTAV GKSILSYMKD DEIEEIWNES NVEKLTEHTI TDFNEFKKCL
NEVRKKRYAV DEQENEIGVR CVGTSIFNYK GEICGAISIS GSIISFTKEK LEEFSKLIIE
YAERISKELG YRE
//
