ID A0Q343_CLONN Unreviewed; 192 AA.
AC A0Q343;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Precorrin-6B methylase/decarboxylase cbiT/cbiE {ECO:0000313|EMBL:ABK62538.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:ABK62538.1};
GN Name=cbiT {ECO:0000313|EMBL:ABK62538.1};
GN OrderedLocusNames=NT01CX_0579 {ECO:0000313|EMBL:ABK62538.1};
OS Clostridium novyi (strain NT).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK62538.1, ECO:0000313|Proteomes:UP000008220};
RN [1] {ECO:0000313|EMBL:ABK62538.1, ECO:0000313|Proteomes:UP000008220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NT {ECO:0000313|EMBL:ABK62538.1,
RC ECO:0000313|Proteomes:UP000008220};
RX PubMed=17115055; DOI=10.1038/nbt1256;
RA Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA Zhou S.;
RT "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT NT.";
RL Nat. Biotechnol. 24:1573-1580(2006).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
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DR EMBL; CP000382; ABK62538.1; -; Genomic_DNA.
DR RefSeq; WP_011723024.1; NC_008593.1.
DR AlphaFoldDB; A0Q343; -.
DR STRING; 386415.NT01CX_0579; -.
DR KEGG; cno:NT01CX_0579; -.
DR PATRIC; fig|386415.7.peg.2083; -.
DR eggNOG; COG2242; Bacteria.
DR HOGENOM; CLU_094143_0_0_9; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000008220; Chromosome.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR009602; CBAR/FAM92.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF06730; FAM92; 1.
DR Pfam; PF13847; Methyltransf_31; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ABK62538.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008220};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABK62538.1}.
FT DOMAIN 32..148
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13847"
SQ SEQUENCE 192 AA; 21733 MW; B3DDAAA99FDC0926 CRC64;
MKYIKDEEFI RGESPMTKEE VRILSISKMG VDENSTVLDV GAGTGSISIQ LSKICNKGEV
IAVEKEEKAV KLINKNKEKF SAHNLKIIKG EALEVCESIK SKFDAIFIGG SGGNIEDIIL
NYEKKLKNKG RIVLNFITIN NLYKAMETLK NISYKVEFIE VSISRSFKNT YMLKANNPIF
IVWGEKNEKM ER
//
