ID A0Q3B3_CLONN Unreviewed; 605 AA.
AC A0Q3B3;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000313|EMBL:ABK60966.1};
GN OrderedLocusNames=NT01CX_0649 {ECO:0000313|EMBL:ABK60966.1};
OS Clostridium novyi (strain NT).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=386415 {ECO:0000313|EMBL:ABK60966.1, ECO:0000313|Proteomes:UP000008220};
RN [1] {ECO:0000313|EMBL:ABK60966.1, ECO:0000313|Proteomes:UP000008220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NT {ECO:0000313|EMBL:ABK60966.1,
RC ECO:0000313|Proteomes:UP000008220};
RX PubMed=17115055; DOI=10.1038/nbt1256;
RA Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA Zhou S.;
RT "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT NT.";
RL Nat. Biotechnol. 24:1573-1580(2006).
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DR EMBL; CP000382; ABK60966.1; -; Genomic_DNA.
DR AlphaFoldDB; A0Q3B3; -.
DR STRING; 386415.NT01CX_0649; -.
DR KEGG; cno:NT01CX_0649; -.
DR PATRIC; fig|386415.7.peg.2153; -.
DR eggNOG; COG0860; Bacteria.
DR HOGENOM; CLU_456125_0_0_9; -.
DR Proteomes; UP000008220; Chromosome.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR CDD; cd02696; MurNAc-LAA; 2.
DR Gene3D; 2.60.40.1220; -; 1.
DR Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 2.
DR InterPro; IPR011081; Big_4.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR002508; MurNAc-LAA_cat.
DR InterPro; IPR032812; SbsA_Ig.
DR PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR Pfam; PF01520; Amidase_3; 2.
DR Pfam; PF07532; Big_4; 1.
DR Pfam; PF13205; Big_5; 1.
DR SMART; SM00646; Ami_3; 2.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008220};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 269..378
FT /note="MurNAc-LAA"
FT /evidence="ECO:0000259|SMART:SM00646"
FT DOMAIN 490..600
FT /note="MurNAc-LAA"
FT /evidence="ECO:0000259|SMART:SM00646"
FT REGION 384..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..413
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 66581 MW; 7031EACCD081AC00 CRC64;
MFLGIMFITL GTYNNVLAST YKNMGQKSNI VLNKHWVIKF NKDVDRNTIN NSSIVLQDEN
NNNIAIDVFY NNSRQVTVFP KNEYKPNTNY TLSIKDSVKS TDGKRIKTPV KLQFSTETVH
IKTINDITEV TGQRANYNLP KTVEAVMSDG SIKNVPVKWN KTSIDTSNAG TFSIEGKVDG
YSRIIVLKLI INPKEITEPQ KDFKVVIDPA CGGNLSASVG PTGVNEKDVN LAIALKLGSM
LKNKGIDVIY TRSNDNVSWG DKEDDNRRIK IANDSNANLF VSINSNSYNA SVNGAETYYC
EGNAMGLKLA SEVQNTLVQA TGARDRGVKE RNFGILKGIK MPGIVVYPGF ITNAREEKLL
KDDSYQNKIA KSIADNVLAN MSGTSLKPSD DVSPSKPIVT PKPPVPVEKP KPSTPSTPSK
RIKVAIDPGH GGYDSGAVGH NGVLEKNVTL AVSLKLGQVL KNSGIDVVYT RTSDKCPWPS
NKNAELQMRC DIANNANADY FVSIHCNSAD TSAATGIETY YDRDSKRGNI LAKNIQNELV
NEFGYKNRGI KPCGFYVVRH TKMQAVLVEL EFISNSNREQ ILNNPKYQQR YAEAIARGIK
DTIGK
//
