ID A0QQW7_MYCS2 Unreviewed; 289 AA.
AC A0QQW7;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=Cyclopropane-fatty-acyl-phospholipid synthase 1 {ECO:0000313|EMBL:ABK73616.1};
DE EC=2.1.1.79 {ECO:0000313|EMBL:ABK73616.1};
GN OrderedLocusNames=MSMEG_0902 {ECO:0000313|EMBL:ABK73616.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK73616.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK73616.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC {ECO:0000256|ARBA:ARBA00010815}.
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DR EMBL; CP000480; ABK73616.1; -; Genomic_DNA.
DR RefSeq; WP_011727278.1; NZ_SIJM01000010.1.
DR RefSeq; YP_885305.1; NC_008596.1.
DR AlphaFoldDB; A0QQW7; -.
DR STRING; 246196.MSMEG_0902; -.
DR PaxDb; 246196-MSMEI_0881; -.
DR GeneID; 66739071; -.
DR KEGG; msm:MSMEG_0902; -.
DR PATRIC; fig|246196.19.peg.892; -.
DR eggNOG; COG2230; Bacteria.
DR OrthoDB; 9782855at2; -.
DR Proteomes; UP000000757; Chromosome.
DR GO; GO:0008825; F:cyclopropane-fatty-acyl-phospholipid synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003333; CMAS.
DR InterPro; IPR047672; CMAS_actinobact.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; NF040660; mycolic_MTase; 1.
DR PANTHER; PTHR43667; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR PANTHER; PTHR43667:SF1; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR Pfam; PF02353; CMAS; 1.
DR PIRSF; PIRSF003085; CMAS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Methyltransferase {ECO:0000313|EMBL:ABK73616.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000757};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABK73616.1}.
FT ACT_SITE 269
FT /evidence="ECO:0000256|PIRSR:PIRSR003085-1"
FT BINDING 33..34
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR003085-2"
FT BINDING 68..76
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR003085-2"
FT BINDING 94..99
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR003085-2"
FT BINDING 123..124
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR003085-2"
SQ SEQUENCE 289 AA; 32913 MW; 3537D9CF573FBB0D CRC64;
MRETLTPNFA DVQAHYDLSD DFFRLFLDPT QTYSCAYFAQ DGMTLEEAQI AKIDLALGKL
GLEPGMTLLD VGCGWGATMR RAVERHDVNV VGLTLSRNQA AHVERMLDDV GSRRSRRVLL
QGWEQFDEPV DRIVSIGAFE HFRHERYDEF FAKAHALLPD DGVMLLHTIC GFHPNHFREA
GIPMTMEMAK FVKFILTEIF PGGQLPSSEM VHDRAGRAGF VVSREQSLQP HYAKTLDIWA
SRLQAHQDEA IAIQSLEVYQ RYMKYLTGCA QLFRDGQVDV VQFTLQKGR
//
