ID A0R337_MYCS2 Unreviewed; 246 AA.
AC A0R337;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE RecName: Full=GDT1 family protein {ECO:0000256|RuleBase:RU365102};
GN OrderedLocusNames=MSMEG_5329 {ECO:0000313|EMBL:ABK73421.1};
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK73421.1, ECO:0000313|Proteomes:UP000000757};
RN [1] {ECO:0000313|EMBL:ABK73421.1, ECO:0000313|Proteomes:UP000000757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU365102}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365102}.
CC -!- SIMILARITY: Belongs to the GDT1 family. {ECO:0000256|ARBA:ARBA00009190,
CC ECO:0000256|RuleBase:RU365102}.
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DR EMBL; CP000480; ABK73421.1; -; Genomic_DNA.
DR RefSeq; WP_003896727.1; NZ_SIJM01000014.1.
DR RefSeq; YP_889575.1; NC_008596.1.
DR AlphaFoldDB; A0R337; -.
DR STRING; 246196.MSMEG_5329; -.
DR PaxDb; 246196-MSMEI_5184; -.
DR GeneID; 66736637; -.
DR KEGG; msm:MSMEG_5329; -.
DR PATRIC; fig|246196.19.peg.5197; -.
DR eggNOG; COG2119; Bacteria.
DR OrthoDB; 5188730at2; -.
DR Proteomes; UP000000757; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR001727; GDT1-like.
DR PANTHER; PTHR12608:SF1; TRANSMEMBRANE PROTEIN 165; 1.
DR PANTHER; PTHR12608; TRANSMEMBRANE PROTEIN HTP-1 RELATED; 1.
DR Pfam; PF01169; UPF0016; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365102};
KW Reference proteome {ECO:0000313|Proteomes:UP000000757};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU365102};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU365102}.
FT TRANSMEM 34..55
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 67..84
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 137..160
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 167..185
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 191..214
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT REGION 225..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..246
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 246 AA; 26144 MW; FD568804B207B614 CRC64;
MLAALALSFG VIFIAELGDK SQLMAMTFAL RYRWWVVLGG ITLATTAVHL ISVAVGHYLG
AALPTHLLGI VAGVAFVFFG LWTLRGDRLS EDEATRAQRT SAPAFFAVTS AFLLAELGDK
TMLATITLAA DNDWVGVWIG STIGMVAADA LAIVVGAIAG KHLPERMIQI AAAVLFLGFG
FFMLLENIWH APALLLVAAS LGIVAALAAM VFALPERLRP QVLRRSSAAA DTEEDTGLRE
PAQREV
//
