ID   A0R5P2_MYCS2            Unreviewed;       289 AA.
AC   A0R5P2;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   RecName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] {ECO:0000256|ARBA:ARBA00016090};
DE            EC=2.6.1.16 {ECO:0000256|ARBA:ARBA00012916};
GN   OrderedLocusNames=MSMEG_6261 {ECO:0000313|EMBL:ABK71222.1};
OS   Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS   smegmatis).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=246196 {ECO:0000313|EMBL:ABK71222.1, ECO:0000313|Proteomes:UP000000757};
RN   [1] {ECO:0000313|EMBL:ABK71222.1, ECO:0000313|Proteomes:UP000000757}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155 {ECO:0000313|Proteomes:UP000000757};
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-
CC         phosphate + L-glutamate; Xref=Rhea:RHEA:13237, ChEBI:CHEBI:29985,
CC         ChEBI:CHEBI:58359, ChEBI:CHEBI:58725, ChEBI:CHEBI:61527; EC=2.6.1.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001031};
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DR   EMBL; CP000480; ABK71222.1; -; Genomic_DNA.
DR   RefSeq; WP_003897683.1; NZ_SIJM01000027.1.
DR   RefSeq; YP_890480.1; NC_008596.1.
DR   AlphaFoldDB; A0R5P2; -.
DR   STRING; 246196.MSMEG_6261; -.
DR   PaxDb; 246196-MSMEI_6099; -.
DR   GeneID; 66737544; -.
DR   KEGG; msm:MSMEG_6261; -.
DR   PATRIC; fig|246196.19.peg.6100; -.
DR   eggNOG; COG0449; Bacteria.
DR   OrthoDB; 9763290at2; -.
DR   Proteomes; UP000000757; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR   InterPro; IPR017932; GATase_2_dom.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   PANTHER; PTHR10937; GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING; 1.
DR   PANTHER; PTHR10937:SF0; GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING); 1.
DR   Pfam; PF13522; GATase_6; 1.
DR   SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR   PROSITE; PS51278; GATASE_TYPE_2; 1.
PE   4: Predicted;
KW   Aminotransferase {ECO:0000256|ARBA:ARBA00022576};
KW   Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962,
KW   ECO:0000313|EMBL:ABK71222.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000757};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          2..289
FT                   /note="Glutamine amidotransferase type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS51278"
SQ   SEQUENCE   289 AA;  30950 MW;  2ED598FD6C41BD49 CRC64;
     MCGIVGLHLR TAELYPRLGE MLTEMLCEMS DRGADSAGVA VYGDPVWSPP GRGCVSVTDL
     AVAPDLGPDV EVVQVDSTYL LSADTPSEDL LERVKAAYPS ALIAGFGADL AVLKGVGHPR
     ALTDAWGLVK AQGWQGVGHT RMATESAVTP SGCHPYTVGP EQCLVHNGSF SNHATIRREL
     RRAGVQFDSE NDTEVGARFV AQQLAAGRDV QTALKALCAT FDGFYTLLVS NRDSFAVVRD
     AIACKPAVIA ETDEWVAMAS EYRALSGLPG VEKARIWEPE PEVVYAWTR
//