ID A0RPX3_CAMFF Unreviewed; 715 AA.
AC A0RPX3;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:ABK82804.1};
GN OrderedLocusNames=CFF8240_1095 {ECO:0000313|EMBL:ABK82804.1};
OS Campylobacter fetus subsp. fetus (strain 82-40).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Campylobacteraceae; Campylobacter.
OX NCBI_TaxID=360106 {ECO:0000313|EMBL:ABK82804.1, ECO:0000313|Proteomes:UP000000760};
RN [1] {ECO:0000313|Proteomes:UP000000760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=82-40 {ECO:0000313|Proteomes:UP000000760};
RA Fouts D.E., Nelson K.E.;
RT "Sequence of Campylobacter fetus subsp. fetus 82-40.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000487; ABK82804.1; -; Genomic_DNA.
DR AlphaFoldDB; A0RPX3; -.
DR KEGG; cff:CFF8240_1095; -.
DR PATRIC; fig|360106.6.peg.1067; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_7; -.
DR Proteomes; UP000000760; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:ABK82804.1};
KW Cilium {ECO:0000313|EMBL:ABK82804.1};
KW Flagellum {ECO:0000313|EMBL:ABK82804.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000000760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 110..133
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 286..315
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT REGION 332..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 78060 MW; 58F67D4B80E5B75B CRC64;
MVAPFLAPFV KAKSLTVVFV IIAILAIIIV PLPSPVLDFF LALSLSISVL IILISIYIPK
PTDLSTFPTL ILIITLFRLS LNIATTRMIL SEGHNGPEAV SEIIASFGQF VVGGNYVIGI
IVFCILVLIN FMVVTKGSTR VSEVQARFTL DAMPGKQMAI DADLNAGLID EQTARSRRQE
IIGEANFYGA MDGSSKFIKG DAVAGIIITI INIIGGFLIG TFQHDLDMAN AAQTYTILTI
GDGLVSQIPG LITSTATAII ITRASKDEDN FAEGVISQLL GEYKTLLIVG FILFVFALVP
GLPTFSLGFM AILFLSIGYI MKQTEEGNLD FSNINKDEKK PQKQGSSTSA DTGGDIKPAK
KSEEEIAKEE QIKIDDILKI EILELDLGYG LLKLADGDLI ERIRAMRRNI AGLLGFLMPK
IRIRDNLQLP PNEYRFKLKG VVIGQGVIYA DKFLAMDSGY VSSDIDGIAT KEPAFGLDAL
WIDQGLKEDA ILSGYTVVDP ASVISTHMSE LVKQNASELL TKQEVQNILD KVKSEYPVVV
EDTLKVASVG LIQKVLKTLL KDNIPIKDML SILEAVGDVS EVSKNLDMII EHVRAALCRV
ITSLYADEKG QLNFYILDAP AQQKLIDSLN YKDGAYHLMI NVAQTSAIVN ALRQKRANRN
ISEQGDMLLC VEPSIRKFIA NIVQNFAIDI VILSFAEIAP NTQFETLGVI EIPEL
//
