ID A0RXX5_CENSY Unreviewed; 374 AA.
AC A0RXX5;
DT 09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Cysteine sulfinate desulfinase/cysteine desulfurase {ECO:0000313|EMBL:ABK78192.1};
DE EC=4.4.1.- {ECO:0000313|EMBL:ABK78192.1};
GN OrderedLocusNames=CENSYa_1572 {ECO:0000313|EMBL:ABK78192.1};
OS Cenarchaeum symbiosum (strain A).
OC Archaea; Nitrososphaerota; Cenarchaeales; Cenarchaeaceae; Cenarchaeum.
OX NCBI_TaxID=414004 {ECO:0000313|EMBL:ABK78192.1, ECO:0000313|Proteomes:UP000000758};
RN [1] {ECO:0000313|EMBL:ABK78192.1, ECO:0000313|Proteomes:UP000000758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A {ECO:0000313|Proteomes:UP000000758};
RX PubMed=17114289; DOI=10.1073/pnas.0608549103;
RA Hallam S.J., Konstantinidis K.T., Putnam N., Schleper C., Watanabe Y.,
RA Sugahara J., Preston C., de la Torre J., Richardson P.M., DeLong E.F.;
RT "Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum
RT symbiosum.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:18296-18301(2006).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU004504};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DP000238; ABK78192.1; -; Genomic_DNA.
DR AlphaFoldDB; A0RXX5; -.
DR STRING; 414004.CENSYa_1572; -.
DR EnsemblBacteria; ABK78192; ABK78192; CENSYa_1572.
DR KEGG; csy:CENSYa_1572; -.
DR PATRIC; fig|414004.10.peg.1439; -.
DR HOGENOM; CLU_003433_0_0_2; -.
DR Proteomes; UP000000758; Chromosome.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.260.50; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000313|EMBL:ABK78192.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000000758}.
FT DOMAIN 3..349
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 374 AA; 39926 MW; A7408F45711557CD CRC64;
MRPEVLEAML PYLEGDYGNP SSIHRQGRTA ERAVDDAREQ AAALIGASPK EIILTSGGTE
SNNMAVLGAR GEPGRNGFVT TSIEHDAVLE PCARLRDRGF ETSTVGPGDD GIVRAAEMAK
AVGPGTSHAS VMTANNEVGT IQPISEIAGI CRERGAVFHT DAVQAAGKVP LDVSELGVDM
LSFSSHKING PKGAGALYVR KGVELDPLIL GGGQERGMRS GTENVAAIAG FGRACEMARE
RLTEDAARVR RMRDRLAERI LGEITHVEYN GSKESRLPGN AHFTFYGVSG EDLLIKLDEY
GLAASTGSAC SVRTQKESHV LRAMGFARER INGSLRLSVG IFNTDEEIDG AVDALTRAVA
ELRRVSPYRA KYGF
//
