ID A0YJ38_LYNSP Unreviewed; 967 AA.
AC A0YJ38;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 24-JAN-2024, entry version 94.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=L8106_01952 {ECO:0000313|EMBL:EAW39039.1};
OS Lyngbya sp. (strain PCC 8106) (Lyngbya aestuarii (strain CCY9616)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Lyngbya.
OX NCBI_TaxID=313612 {ECO:0000313|EMBL:EAW39039.1, ECO:0000313|Proteomes:UP000000737};
RN [1] {ECO:0000313|EMBL:EAW39039.1, ECO:0000313|Proteomes:UP000000737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC8106 {ECO:0000313|Proteomes:UP000000737};
RA Stal L., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAW39039.1}.
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DR EMBL; AAVU01000002; EAW39039.1; -; Genomic_DNA.
DR RefSeq; WP_009782494.1; NZ_AAVU01000002.1.
DR AlphaFoldDB; A0YJ38; -.
DR eggNOG; COG4191; Bacteria.
DR OrthoDB; 9814202at2; -.
DR Proteomes; UP000000737; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF50; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08447; PAS_3; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:EAW39039.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000000737};
KW Transferase {ECO:0000313|EMBL:EAW39039.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 543..616
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 617..669
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 710..967
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 653..701
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 967 AA; 110614 MW; F22F21A060AC841C CRC64;
MNSKQLQRLL IFYSAIGIFT ISVLVAVLSI FPLYQQLRKS EERNLQSALK TRKLAVEEFL
SGVKDITAQI ASSTQAKQLL EIYNQNPNDR KSAATNVTLF LTDALNQTEY LAGITRLDQN
NQFMAQVGLS IPKSFWKFSA VNSQDTQISN PIRLNDKFYL IVIQPIFDLK QEQIGTDLVL
FEMDRLKEII VTDYTGLGKA EQVFLGTLED QKVKLLLSSN NENETLLKPI IEALEKTVVS
QESGFTVVKG KFWNHAQVII FEPLSEFNWG LVIKIDRQEL YAPVNRQLMT IGMVTIIFSL
LGAGGMVLLL RPLAGRAIIQ TDELEKQLQE KSLTLRELNY TQEQLLLEIR DRKFAQTELQ
KRAEQLRNHN TVLIGIAQQR AVNQGDLLTA AQAITEATAK ILEVDRVGVW LYNEDKTHLK
CFDLYQKKLN KHEREGVIRH NDYPAYFDAI NIQDSIAASD ARNDPRTCEF LSNYFIPNNI
FSLLDSTIRI GGKIVGVICI EQCNQIQNWT PEDEIFVRSI GNIISLAIEA RNHQKAEIAL
QESERMFRQL AESIDSVFWI SDPDGKEIYY VSPAYERVWG RPCRQVYEQP QSFLESIHSE
DREGVILALT KQVSGGYEEE YRIVKPNGEI RWIYDRGFPI KNDQGKIDRV TGIATDITER
KQAENALRES EAQLREQKQQ LQQTLKELQR TQAQMIQNEK MSSLGQMVAG IAHEINNPVN
FIHGNIVHAA DYIRDLLSLI QLYQQYYPHP HPDIEIEIEA IELDFLQEDI KKLLKSMQVG
TERIREIVKS LRIFSRLDES EIKEVDLHEG LESTLMILHN RFKAKSIYPG IKVIKEYDKI
PRITCYSGHL NQVFMNILSN AIDAIEDAQS FQSPEEIQHN PGCIRIKTQQ IAPNWIQILI
ADNGQGMSEE VRTRLFDPFF TTKPIGKGTG LGLSISYQVI IEKHKGNIEC DSILGQGTEF
RIQIPIR
//
